Xylarianaphthol-1

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565436

CAS#: 1620084-30-1

Description: Xylarianaphthol-1 is an activator of p21 promoter in a p53-independent manner.


Price and Availability

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Xylarianaphthol-1 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 565436
Name: Xylarianaphthol-1
CAS#: 1620084-30-1
Chemical Formula: C21H14O4
Exact Mass: 330.0892
Molecular Weight: 330.34
Elemental Analysis: C, 76.36; H, 4.27; O, 19.37


Synonym: Xylarianaphthol1; Xylarianaphthol 1; Xylarianaphthol-1

IUPAC/Chemical Name: 4-Methoxydinaphtho[1,2-b:1',2'-d]furan-5,8-diol

InChi Key: WJWZJXZBHYSKCI-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H14O4/c1-24-16-7-3-5-12-19-13-9-8-11-4-2-6-14(22)18(11)21(13)25-17(19)10-15(23)20(12)16/h2-10,22-23H,1H3

SMILES Code: OC1=C2C(OC)=CC=CC2=C3C4=CC=C5C=CC=C(O)C5=C4OC3=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01


References

1: Kotoku N, Higashimoto K, Kurioka M, Arai M, Fukuda A, Sumii Y, Sowa Y, Sakai T, Kobayashi M. Xylarianaphthol-1, a novel dinaphthofuran derivative, activates p21 promoter in a p53-independent manner. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3389-91. doi: 10.1016/j.bmcl.2014.05.083. Epub 2014 Jun 4. PubMed PMID: 24939757.