BC-1485

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565395

CAS#: 2035085-19-7

Description: BC-1485 is a first-in-class inhibitor of Fibrosis-inducing E3 ligase 1 (FIEL1 ), which disrupts FIEL1-directed PIAS4 ubiquitination.


Price and Availability

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BC-1485 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 565395
Name: BC-1485
CAS#: 2035085-19-7
Chemical Formula: C19H21N5O5S
Exact Mass: 431.1263
Molecular Weight: 431.47
Elemental Analysis: C, 52.89; H, 4.91; N, 16.23; O, 18.54; S, 7.43


Synonym: BC1485; BC 1485; BC-1485

IUPAC/Chemical Name: N-(1-(Dimethylamino)-1-oxopropan-2-yl)-4-((2-oxo-2,3-dihydro-1H-benzo[d]imidazole)-5-sulfonamido)benzamide

InChi Key: ZDIJTGCDKBHHPD-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H21N5O5S/c1-11(18(26)24(2)3)20-17(25)12-4-6-13(7-5-12)23-30(28,29)14-8-9-15-16(10-14)22-19(27)21-15/h4-11,23H,1-3H3,(H,20,25)(H2,21,22,27)

SMILES Code: O=C(NC(C)C(N(C)C)=O)C1=CC=C(NS(=O)(C2=CC=C(C(N3)=C2)NC3=O)=O)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01


References

1: Lear T, Chen BB. Therapeutic targets in fibrotic pathways. Cytokine. 2016 Dec;88:193-195. doi: 10.1016/j.cyto.2016.09.008. Epub 2016 Sep 19. PubMed PMID: 27658114; PubMed Central PMCID: PMC5119757.