AMG-510 racemate
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 207099

CAS#: 2296729-00-3 (racemate)

Description: AMG-510 racemate is a racemic mixture of AMB-510, which is a potent KRAS G12C covalent inhibitor. AMG-510 selectively targets the KRAS p.G12C mutant, at either the DNA, RNA or protein level, and prevents, through an as of yet not elucidated manner, expression of and/or tumor cell signaling through the KRAS p.G12C mutant. This may inhibit growth in KRAS p.G12C-expressing tumor cells


Price and Availability

Size
Price

100mg
USD 950
1g
USD 3950
Size
Price

200mg
USD 1750
2g
USD 7250
Size
Price

500mg
USD 2850

AMG-510 racemate, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 207099
Name: AMG-510 racemate
CAS#: 2296729-00-3 (racemate)
Chemical Formula: C30H30F2N6O3
Exact Mass: 560.2347
Molecular Weight: 560.6058
Elemental Analysis: C, 64.28; H, 5.39; F, 6.78; N, 14.99; O, 8.56


Related CAS #: 2296729-00-3 (racemate)   2252403-56-6    

Synonym: AMG-510 racemate; AMG 510; AMG-510; AMG510;

IUPAC/Chemical Name: 4-(4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one

InChi Key: NXQKSXLFSAEQCZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8-7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1,12-13,15H2,2-5H3

SMILES Code: O=C1N(C2=C(C)C=CN=C2C(C)C)C3=NC(C4=C(O)C=CC=C4F)=C(F)C=C3C(N5C(C)CN(C(C=C)=O)CC5)=N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01