A-687136

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MedKoo CAT#: 573573

CAS#: Unknown

Description: A-687136 is an H3 antagonist which may play a role in cognition.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-03-29. Prices are subject to change without notice.

A-687136 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 573573
Name: A-687136
CAS#: Unknown
Chemical Formula: C19H21N3O
Exact Mass: 307.1685
Molecular Weight: 307.4
Elemental Analysis: C, 74.24; H, 6.89; N, 13.67; O, 5.20


Synonym: A-687136, A687136, A 687136

IUPAC/Chemical Name: (R)-2-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)pyrazine

InChi Key: HCAQEFBWQFNUAJ-CQSZACIVSA-N

InChi Code: InChI=1S/C19H21N3O/c1-14-3-2-9-22(14)10-6-17-12-16-11-15(4-5-19(16)23-17)18-13-20-7-8-21-18/h4-5,7-8,11-14H,2-3,6,9-10H2,1H3/t14-/m1/s1

SMILES Code: C[C@H]1N(CCC2=CC3=C(C=CC(C4=CN=CC=N4)=C3)O2)CCC1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Cowart M, Gfesser GA, Browman KE, Faghih R, Miller TR, Milicic I, Baranowski JL, Krueger KM, Witte DG, Molesky AL, Komater VA, Buckley MJ, Diaz GJ, Gagne GD, Zhou D, Deng X, Pan L, Roberts EM, Diehl MS, Wetter JM, Marsh KC, Fox GB, Brioni JD, Esbenshade TA, Hancock AA. Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity. Biochem Pharmacol. 2007 Apr 15;73(8):1243-55. Epub 2007 Feb 23. PubMed PMID: 17371699.