WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573562

CAS#: Unknown

Description: Verongamine is a bromotyrosine-derived histamine H3-antagonist from the marine sponge Verongula gigantea.

Chemical Structure

CAS# Unknown

Theoretical Analysis

MedKoo Cat#: 573562
Name: Verongamine
CAS#: Unknown
Chemical Formula: C15H17BrN4O3
Exact Mass: 380.0484
Molecular Weight: 381.23
Elemental Analysis: C, 47.26; H, 4.49; Br, 20.96; N, 14.70; O, 12.59

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Verongamine

IUPAC/Chemical Name: (E)-N-(2-(1H-imidazol-4-yl)ethyl)-3-(3-bromo-4-methoxyphenyl)-2-(hydroxyimino)propanamide


InChi Code: InChI=1S/C15H17BrN4O3/c1-23-14-3-2-10(6-12(14)16)7-13(20-22)15(21)18-5-4-11-8-17-9-19-11/h2-3,6,8-9,22H,4-5,7H2,1H3,(H,17,19)(H,18,21)/b20-13+


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 381.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Boehlow TR, Harburn JJ, Spilling CD. Approaches to the synthesis of some tyrosine-derived marine sponge metabolites: synthesis of verongamine and purealidin N. J Org Chem. 2001 May 4;66(9):3111-8. PubMed PMID: 11325276.

2: Ali SM, Tedford CE, Gregory R, Yates SL, Phillips JG. New acetylene based histamine H3 receptor antagonists derived from the marine natural product verongamine. Bioorg Med Chem Lett. 1998 May 19;8(10):1133-8. PubMed PMID: 9871722.

3: Mierzwa R, King A, Conover MA, Tozzi S, Puar MS, Patel M, Coval SJ, Pomponi SA. Verongamine, a novel bromotyrosine-derived histamine H3-antagonist from the marine sponge Verongula gigantea. J Nat Prod. 1994 Jan;57(1):175-7. PubMed PMID: 8158162.