BLU-782
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555504

CAS#: 2141955-96-4

Description: BLU-782, also known as ALK2-IN-1, is an oral active ALK2 inhibitor, designed to selectively target the mutant FOP receptor (ACVR1/ALK2), the underlying cause of FOP. In FOP mice, BLU-782 prevented the formation of injury-induced heterotopic ossification (HO) and tissue swelling (edema). BLU-782 also prevented the formation of HO following surgery in FOP mice.


Price and Availability

Size
Price

50mg
USD 750
500mg
USD 2950
Size
Price

100mg
USD 1250
1g
USD 3650
Size
Price

200mg
USD 1950
2g
USD 6450

BLU-782, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555504
Name: BLU-782
CAS#: 2141955-96-4
Chemical Formula: C31H42N6O4
Exact Mass: 562.3268
Molecular Weight: 562.715
Elemental Analysis: C, 66.17; H, 7.52; N, 14.94; O, 11.37


Synonym: BLU-782; BLU 782; BLU782; ALK2-IN-1; ALK2-IN 1; ALK2-IN1;

IUPAC/Chemical Name: 1-Piperazinecarboxylic acid, 4-[6-[5-[4-ethoxy-1-(1-methylethyl)-4-piperidinyl]-2-pyridinyl]pyrrolo[1,2-b]pyridazin-4-yl]-, (3R)-tetrahydro-3-furanyl ester

InChi Key: SWVYYNLRVIYURK-AREMUKBSSA-N

InChi Code: InChI=1S/C31H42N6O4/c1-4-40-31(9-12-34(13-10-31)23(2)3)25-5-6-27(32-20-25)24-19-29-28(7-11-33-37(29)21-24)35-14-16-36(17-15-35)30(38)41-26-8-18-39-22-26/h5-7,11,19-21,23,26H,4,8-10,12-18,22H2,1-3H3/t26-/m1/s1

SMILES Code: O=C(N1CCN(C2=CC=NN3C2=CC(C4=NC=C(C5(OCC)CCN(C(C)C)CC5)C=C4)=C3)CC1)O[C@H]6COCC6


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300