XS018661

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565238

CAS#: NONE

Description: XS018661 is the first-in-class dual inhibitor of ENL (Kd = 754 ± 45 nM) and its paralog AF9 (Kd = 523 ± 53 nM).


Price and Availability

Size
Price

Size
Price

Size
Price

XS018661 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 565238
Name: XS018661
CAS#: NONE
Chemical Formula: C22H24N4O3
Exact Mass: 392.1848
Molecular Weight: 392.46
Elemental Analysis: C, 67.33; H, 6.16; N, 14.28; O, 12.23


Synonym: ENL/AF9-IN-1; XS 018661; XS-018661; XS018661

IUPAC/Chemical Name: methyl 4-((2-(piperidin-1-ylmethyl)-1H-benzo[d]imidazol-5-yl)carbamoyl)benzoate

InChi Key: UVAMTJLXRMVTBI-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H24N4O3/c1-29-22(28)16-7-5-15(6-8-16)21(27)23-17-9-10-18-19(13-17)25-20(24-18)14-26-11-3-2-4-12-26/h5-10,13H,2-4,11-12,14H2,1H3,(H,23,27)(H,24,25)

SMILES Code: O=C(OC)C1=CC=C(C(NC2=CC=C3NC(CN4CCCCC4)=NC3=C2)=O)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300