AKI-7169
new
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407989

CAS#: 879127-16-9

Description: AKI-7169, also known as Aurora Kinase Inhibitor III, is a potent Aurora Kinase Inhibitor (IC50 = 42 nM). .


Price and Availability

Size
Price

100mg
USD 1450
1g
USD 3650
Size
Price

200mg
USD 1950
2g
USD 5950
Size
Price

500mg
USD 2950

AKI-7169, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 407989
Name: AKI-7169
CAS#: 879127-16-9
Chemical Formula: C21H18F3N5O
Exact Mass: 413.1463
Molecular Weight: 413.4042
Elemental Analysis: C, 61.01; H, 4.39; F, 13.79; N, 16.94; O, 3.87


Synonym: Aurora Kinase Inhibitor III; AKI-7169; AKI 7169; AKI7169;

IUPAC/Chemical Name: N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-cyclopropanecarboxamide

InChi Key: RDTDWGQDFJPTPD-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H18F3N5O/c22-21(23,24)14-3-1-4-15(11-14)26-18-9-10-25-20(29-18)28-17-6-2-5-16(12-17)27-19(30)13-7-8-13/h1-6,9-13H,7-8H2,(H,27,30)(H2,25,26,28,29)

SMILES Code: O=C(C1CC1)NC2=CC=CC(NC3=NC=CC(NC4=CC=CC(C(F)(F)F)=C4)=N3)=C2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300


References

Zhang, Q., Liu, Y., Gao, F., et al. Discovery of EGFR selective 4,6-disubstituted pyrimidines from a combinatorial kinase-directed heterocycle library J. Am. Chem. Soc. 128(7), 2182-2183 (2006).