CA140

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565196

CAS#: NONE

Description: CA140 is an inhibitor of the neuroinflammatory response in wild-type mice and a mouse model of Alzheimer's disease (AD).


Price and Availability

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Price

Size
Price

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Price

CA140 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 565196
Name: CA140
CAS#: NONE
Chemical Formula: C16H18N2O3
Exact Mass: 286.1317
Molecular Weight: 286.33
Elemental Analysis: C, 67.12; H, 6.34; N, 9.78; O, 16.76


Synonym: Non-self-polymerizing analog of dopamine (DA); CA-140; CA 140; CA140

IUPAC/Chemical Name: N-(3,4-Dihydroxyphenethyl)-2-(methylamino)benzamide

InChi Key: UQPZVGMQOFXKPE-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H18N2O3/c1-17-13-5-3-2-4-12(13)16(21)18-9-8-11-6-7-14(19)15(20)10-11/h2-7,10,17,19-20H,8-9H2,1H3,(H,18,21)

SMILES Code: O=C(NCCC1=CC=C(O)C(O)=C1)C2=CC=CC=C2NC


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300


References

1: Lee JY, Nam JH, Nam Y, Nam HY, Yoon G, Ko E, Kim SB, Bautista MR, Capule CC, Koyanagi T, Leriche G, Choi HG, Yang J, Kim J, Hoe HS. The small molecule CA140 inhibits the neuroinflammatory response in wild-type mice and a mouse model of AD. J Neuroinflammation. 2018 Oct 11;15(1):286. doi: 10.1186/s12974-018-1321-3. PubMed PMID: 30309372; PubMed Central PMCID: PMC6182807.