AAL1

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MedKoo CAT#: 565194

CAS#: 868215-90-1

Description: AAL1 is an inhibitor of dark-grown Arabidopsis thaliana seedlings, functioning through auxin receptor Transport Inhibitor Response1 (TIR1) and depending on auxin influx and efflux carriers.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-04-01. Prices are subject to change without notice.

AAL1 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 565194
Name: AAL1
CAS#: 868215-90-1
Chemical Formula: C15H18N2O3S
Exact Mass: 306.1038
Molecular Weight: 306.38
Elemental Analysis: C, 58.80; H, 5.92; N, 9.14; O, 15.67; S, 10.46


Synonym: Auxin Activity Like 1; AAL-1; AAL 1; AAL1

IUPAC/Chemical Name: N-(4-Ethylphenyl)-2-(2-methyl-3,5-dioxothiomorpholino)acetamide

InChi Key: RPOCQUTXCSLYFJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H18N2O3S/c1-3-11-4-6-12(7-5-11)16-13(18)8-17-14(19)9-21-10(2)15(17)20/h4-7,10H,3,8-9H2,1-2H3,(H,16,18)

SMILES Code: O=C(NC1=CC=C(CC)C=C1)CN2C(C(C)SCC2=O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Li W, Li H, Xu P, Xie Z, Ye Y, Li L, Li D, Zhang Y, Li L, Zhao Y. Identification of Auxin Activity Like 1, a chemical with weak functions in auxin signaling pathway. Plant Mol Biol. 2018 Oct;98(3):275-287. doi: 10.1007/s11103-018-0779-9. Epub 2018 Oct 11. PubMed PMID: 30311174.

2: Taira Y, Okegawa Y, Sugimoto K, Abe M, Miyoshi H, Shikanai T. Antimycin A-like molecules inhibit cyclic electron transport around photosystem I in ruptured chloroplasts. FEBS Open Bio. 2013 Sep 30;3:406-10. doi: 10.1016/j.fob.2013.09.007. eCollection 2013. PubMed PMID: 24251103; PubMed Central PMCID: PMC3821020.

3: Raghavan KS, Gray DB, Scholz TH, Nemeth GA, Hussain MA. Degradation kinetics of DMP 777, an elastase inhibitor. Pharm Res. 1996 Dec;13(12):1815-20. PubMed PMID: 8987077.