WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 565172
CAS#: 251310-57-3
Description: TR-IN-1-850 is a selective blocker of T3 binding to both TRα and TRβ.
MedKoo Cat#: 565172
Name: TR-IN-1-850
CAS#: 251310-57-3
Chemical Formula: C21H20F3N5O4
Exact Mass: 463.1467
Molecular Weight: 463.42
Elemental Analysis: C, 54.43; H, 4.35; F, 12.30; N, 15.11; O, 13.81
Synonym: Thyroid Hormone Receptor Antagonist (1-850); TR-IN 1-850; TR IN-1-850; TR-IN-1 850; TR-IN-1-850
IUPAC/Chemical Name: 2-[1-(4-Nitrophenyl)-4-piperidinylidene]-acetic acid-2-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]hydrazide
InChi Key: CZMAYVNXNKBQKX-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H20F3N5O4/c22-21(23,24)15-2-1-3-16(13-15)25-20(31)27-26-19(30)12-14-8-10-28(11-9-14)17-4-6-18(7-5-17)29(32)33/h1-7,12-13H,8-11H2,(H,26,30)(H2,25,27,31)
SMILES Code: O=C(NNC(NC1=CC=CC(C(F)(F)F)=C1)=O)/C=C2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC/2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 463.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
