BC-11 hydrobromide
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565139

CAS#: 443776-49-6

Description: BC-11 hydrobromide is an inhibitor of Urokinase-Plasminogen Activator (uPa) which induces additional impairment of mitochondrial activity, the production of reactive oxygen species, and promotion of apoptosis.


Price and Availability

Size
Price

1mg
USD 230
Size
Price

5mg
USD 465
Size
Price

BC-11 hydrobromide, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data, and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 565139
Name: BC-11 hydrobromide
CAS#: 443776-49-6
Chemical Formula: C8H12BBrN2O2S
Exact Mass: 289.9896
Molecular Weight: 290.97
Elemental Analysis: C, 33.02; H, 4.16; B, 3.72; Br, 27.46; N, 9.63; O, 11.00; S, 11.02


Synonym: BC11 hydrobromide; BC-11 hydrobromide; BC 11 hydrobromide; BC-11 HBr

IUPAC/Chemical Name: (4-((Carbamimidoylthio)methyl)phenyl)boronic acid hydrobromide

InChi Key: PAFZAMOVHIRQOD-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H11BN2O2S.BrH/c10-8(11)14-5-6-1-3-7(4-2-6)9(12)13;/h1-4,12-13H,5H2,(H3,10,11);1H

SMILES Code: NC(SCC1=CC=C(B(O)O)C=C1)=N.[H]Br


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300


References

1: Longo A, Librizzi M, Chuckowree IS, Baltus CB, Spencer J, Luparello C. Cytotoxicity of the Urokinase-Plasminogen Activator Inhibitor Carbamimidothioic Acid (4-Boronophenyl) Methyl Ester Hydrobromide (BC-11) on Triple-Negative MDA-MB231 Breast Cancer Cells. Molecules. 2015 May 28;20(6):9879-89. doi: 10.3390/molecules20069879. PubMed PMID: 26029857; PubMed Central PMCID: PMC6272237.