B-TPMF

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565061

CAS#: 477865-65-9

Description: B-TPMF is the first small-molecule inhibitor with significant selectivity among the KCa2 channel subtypes.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-03-30. Prices are subject to change without notice.

B-TPMF is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 565061
Name: B-TPMF
CAS#: 477865-65-9
Chemical Formula: C19H24N6O2
Exact Mass: 368.1961
Molecular Weight: 368.44
Elemental Analysis: C, 61.94; H, 6.57; N, 22.81; O, 8.68


Synonym: BTPMF; B-TPMF; B TPMF

IUPAC/Chemical Name: N-{7-[1-(4-tert-Butyl-phenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-N'-methoxy-formamidine

InChi Key: HJKSIPKXGWOSBM-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H24N6O2/c1-13(27-15-8-6-14(7-9-15)19(2,3)4)16-10-11-20-18-23-17(24-25(16)18)21-12-22-26-5/h6-13H,1-5H3,(H,21,22,24)

SMILES Code: CO/N=C/NC1=NN2C(C(OC3=CC=C(C(C)(C)C)C=C3)C)=CC=NC2=N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Hougaard C, Hammami S, Eriksen BL, Sørensen US, Jensen ML, Strøbæk D, Christophersen P. Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1 subtype. Mol Pharmacol. 2012 Feb;81(2):210-9. doi: 10.1124/mol.111.074252. Epub 2011 Nov 1. PubMed PMID: 22046005.