MedKoo Biosciences

TAI-95
featured

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565057

CAS#: 1438638-83-5

Description: TAI-95 is an inhibitor of highly expressed cancer protein 1 (Hec1).

Chemical Structure

TAI-95

CAS# 1438638-83-5

Instruction

Theoretical Analysis

MedKoo Cat#: 565057
Name: TAI-95
CAS#: 1438638-83-5
Chemical Formula: C24H23N5O3S2
Exact Mass: 493.12
Molecular Weight: 493.600
Elemental Analysis: C, 58.40; H, 4.70; N, 14.19; O, 9.72; S, 12.99

Price and Availability

Size	Price	Availability	Quantity
5mg	USD 1455
10mg	USD 2765
25mg	USD 6200
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: TAI95; TAI 95; TAI-95

IUPAC/Chemical Name: N-[4-[4-[[5-(2-Methoxyethoxy)-2-pyrazinyl]thio]-2,6-dimethylphenyl]-2-thiazolyl]-4-pyridinecarboxamide

InChi Key: ICECVTFTHRPNOE-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H23N5O3S2/c1-15-10-18(34-21-13-26-20(12-27-21)32-9-8-31-3)11-16(2)22(15)19-14-33-24(28-19)29-23(30)17-4-6-25-7-5-17/h4-7,10-14H,8-9H2,1-3H3,(H,28,29,30)

SMILES Code: O=C(C1=CC=NC=C1)NC2=NC(C3=C(C)C=C(SC4=NC=C(OCCOC)N=C4)C=C3C)=CS2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Product Data

Instruction:

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 493.600000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

1: Huang LY, Chang CC, Lee YS, Huang JJ, Chuang SH, Chang JM, Kao KJ, Lau GM, Tsai PY, Liu CW, Lin HS, Gish RG, Lau JY. Inhibition of Hec1 as a novel approach for treatment of primary liver cancer. Cancer Chemother Pharmacol. 2014 Sep;74(3):511-20. doi: 10.1007/s00280-014-2540-7. Epub 2014 Jul 20. PubMed PMID: 25038613. 2: Huang LY, Chang CC, Lee YS, Chang JM, Huang JJ, Chuang SH, Kao KJ, Lau GM, Tsai PY, Liu CW, Lin HS, Lau JY. Activity of a novel Hec1-targeted anticancer compound against breast cancer cell lines in vitro and in vivo. Mol Cancer Ther. 2014 Jun;13(6):1419-30. doi: 10.1158/1535-7163.MCT-13-0700. Epub 2014 Apr 2. PubMed PMID: 24694948. 3: Galvão KN, Federico P, De Vries A, Schuenemann GM. Economic comparison of reproductive programs for dairy herds using estrus detection, timed artificial insemination, or a combination. J Dairy Sci. 2013 Apr;96(4):2681-2693. doi: 10.3168/jds.2012-5982. Epub 2013 Feb 15. PubMed PMID: 23415521.

Your view history

TAI-95 featured