IBPR002

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565055

CAS#: 1192754-38-3

Description: IBPR002 is an aurora kinase inhibitor which reveals mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.

Price and Availability

Pricing updated 2021-01-21. Prices are subject to change without notice.

IBPR002 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure

Theoretical Analysis

MedKoo Cat#: 565055
Name: IBPR002
CAS#: 1192754-38-3
Chemical Formula: C34H36N6O4
Exact Mass: 592.2798
Molecular Weight: 592.7
Elemental Analysis: C, 68.90; H, 6.12; N, 14.18; O, 10.80

Synonym: IBPR-002; IBPR 002; IBPR002

IUPAC/Chemical Name: 1-{4-[2-(6-{4-[2-(4-Hydroxy-piperidin-1-yl)-ethoxy]-phenyl}-furo[2,3-d]pyrimidin-4-ylamino)-ethyl]-phenyl}-3-phenyl-urea

InChi Key: WEVRAOPLGYJTLY-UHFFFAOYSA-N

InChi Code: InChI=1S/C34H36N6O4/c41-28-15-18-40(19-16-28)20-21-43-29-12-8-25(9-13-29)31-22-30-32(36-23-37-33(30)44-31)35-17-14-24-6-10-27(11-7-24)39-34(42)38-26-4-2-1-3-5-26/h1-13,22-23,28,41H,14-21H2,(H,35,36,37)(H2,38,39,42)

SMILES Code: O=C(NC1=CC=CC=C1)NC2=CC=C(CCNC3=C4C(OC(C5=CC=C(OCCN6CCC(O)CC6)C=C5)=C4)=NC=N3)C=C2

Technical Data

Appearance:

Solid powder

Purity:

>98% (or refer to the Certificate of Analysis)

Shipping Condition:

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:

Soluble in DMSO

Shelf Life:

>3 years if stored properly

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

2934.99.9001

References

1: Wu JM, Chen CT, Coumar MS, Lin WH, Chen ZJ, Hsu JT, Peng YH, Shiao HY, Lin WH, Chu CY, Wu JS, Lin CT, Chen CP, Hsueh CC, Chang KY, Kao LP, Huang CY, Chao YS, Wu SY, Hsieh HP, Chi YH. Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules. Proc Natl Acad Sci U S A. 2013 May 7;110(19):E1779-87. doi: 10.1073/pnas.1220523110. Epub 2013 Apr 22. PubMed PMID: 23610398; PubMed Central PMCID: PMC3651446.

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