L2-b
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573450

CAS#: 52688-60-5

Description: L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggregation studies, L2-b inhibits metal-induced Aβ aggregation, and also promotes the dissociation of Ab aggregates in homogenates of human AD brain samples.


Chemical Structure

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L2-b
CAS# 52688-60-5

Theoretical Analysis

MedKoo Cat#: 573450
Name: L2-b
CAS#: 52688-60-5
Chemical Formula: C14H17N3
Exact Mass: 227.1422
Molecular Weight: 227.31
Elemental Analysis: C, 73.98; H, 7.54; N, 18.49

Price and Availability

Size Price Availability Quantity
5.0mg USD 285.0 2 Weeks
25.0mg USD 875.0 2 Weeks
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Synonym: L2-b

IUPAC/Chemical Name: N,N-Dimethyl-N′-(2-pyridinylmethyl)-1,4-benzenediamine

InChi Key: RIKLBFYMQFBFJF-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H17N3/c1-17(2)14-8-6-12(7-9-14)16-11-13-5-3-4-10-15-13/h3-10,16H,11H2,1-2H3

SMILES Code: CN(C)C1=CC=C(NCC2=NC=CC=C2)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 227.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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L2-b

5.0mg / USD 285.0