WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565025

CAS#: 925238-89-7

Description: JMV-2959 is a GHS-R1a antagonist.

Chemical Structure

CAS# 925238-89-7

Theoretical Analysis

MedKoo Cat#: 565025
Name: JMV-2959
CAS#: 925238-89-7
Chemical Formula: C30H32N6O2
Exact Mass: 508.2587
Molecular Weight: 508.63
Elemental Analysis: C, 70.84; H, 6.34; N, 16.52; O, 6.29

Price and Availability

Size Price Availability Quantity
10.0mg USD 450.0 2 Weeks
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Synonym: JMV2959; JMV 2959; JMV-2959

IUPAC/Chemical Name: N-[(R)-1-[4-(4-Methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]-2-aminoacetamide


InChi Code: InChI=1S/C30H32N6O2/c1-38-24-14-11-22(12-15-24)20-36-28(16-13-21-7-3-2-4-8-21)34-35-30(36)27(33-29(37)18-31)17-23-19-32-26-10-6-5-9-25(23)26/h2-12,14-15,19,27,32H,13,16-18,20,31H2,1H3,(H,33,37)/t27-/m1/s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 508.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Rodriguez JA, Fehrentz JA, Martinez J, Ben Haj Salah K, Wellman PJ. The GHR-R antagonist JMV 2959 neither induces malaise nor alters the malaise property of LiCl in the adult male rat. Physiol Behav. 2018 Jan 1;183:46-48. doi: 10.1016/j.physbeh.2017.10.017. Epub 2017 Oct 19. PubMed PMID: 29056353.

2: Abtahi S, Howell E, Currie PJ. Accumbal ghrelin and glucagon-like peptide 1 signaling in alcohol reward in female rats. Neuroreport. 2018 Aug 15;29(12):1046-1053. doi: 10.1097/WNR.0000000000001071. PubMed PMID: 29927808.

3: Havlickova T, Charalambous C, Lapka M, Puskina N, Jerabek P, Sustkova-Fiserova M. Ghrelin Receptor Antagonism of Methamphetamine-Induced Conditioned Place Preference and Intravenous Self-Administration in Rats. Int J Mol Sci. 2018 Sep 26;19(10). pii: E2925. doi: 10.3390/ijms19102925. PubMed PMID: 30261633; PubMed Central PMCID: PMC6213741.

4: Terrill SJ, Wall KD, Medina ND, Maske CB, Williams DL. Lateral septum growth hormone secretagogue receptor affects food intake and motivation for sucrose reinforcement. Am J Physiol Regul Integr Comp Physiol. 2018 Jul 1;315(1):R76-R83. doi: 10.1152/ajpregu.00339.2017. Epub 2018 Mar 28. PubMed PMID: 29590554; PubMed Central PMCID: PMC6087886.

5: Sustkova-Fiserova M, Charalambous C, Havlickova T, Lapka M, Jerabek P, Puskina N, Syslova K. Alterations in Rat Accumbens Endocannabinoid and GABA Content during Fentanyl Treatment: The Role of Ghrelin. Int J Mol Sci. 2017 Nov 22;18(11). pii: E2486. doi: 10.3390/ijms18112486. PubMed PMID: 29165386; PubMed Central PMCID: PMC5713452.


10.0mg / USD 450.0