Zeaxanthin
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MedKoo CAT#: 555463

CAS#: 144-68-3

Description: Zeaxanthin is one of the most common carotenoid alcohols found in nature. It is important in the xanthophyll cycle. Synthesized in plants and some micro-organisms, it is the pigment that gives paprika (made from bell peppers), corn, saffron, wolfberries, and many other plants and microbes their characteristic color.


Chemical Structure

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Zeaxanthin
CAS# 144-68-3

Theoretical Analysis

MedKoo Cat#: 555463
Name: Zeaxanthin
CAS#: 144-68-3
Chemical Formula: C40H56O2
Exact Mass: 568.428
Molecular Weight: 568.886
Elemental Analysis: C, 84.45; H, 9.92; O, 5.62

Price and Availability

Size Price Availability Quantity
2.0g USD 150.0 2 Weeks
5.0g USD 250.0 2 Weeks
10.0g USD 450.0 2 Weeks
20.0g USD 750.0 2 Weeks
50.0g USD 1250.0 2 Weeks
100.0g USD 1850.0 2 Weeks
500.0g USD 3850.0 2 Weeks
1.0kg USD 6950.0 2 Weeks
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Synonym: beta-Carotene-3,3'-diol; Zeaxanthin; Anchovyxanthin; Xanthophyll 3; Zeaxanthol;

IUPAC/Chemical Name: 4-[18-(4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl)-3,7,12,16-tetramethyl-octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-cyclohex-3-en-1-ol

InChi Key: JKQXZKUSFCKOGQ-DKLMTRRASA-N

InChi Code: InChI=1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-24,35-36,41-42H,25-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+

SMILES Code: OC1CC(C)=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CC(O)CC2(C)C)C(C)(C)C1

Appearance: Solid powder

Purity: >80% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 568.886 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Additional Information

Several observational studies have provided preliminary evidence for high dietary intake of foods including lutein and zeaxanthin with lower incidence of age-related macular degeneration (AMD), most notably the Age-Related Eye Disease Study (AREDS2). Because foods high in one of these carotenoids tend to be high in the other, research does not separate effects of one from the other. Three subsequent meta-analyses of dietary lutein and zeaxanthin concluded that these carotenoids lower the risk of progression from early stage AMD to late stage AMD. A 2017 Cochrane review of 19 studies from several countries concluded that dietary supplements containing zeaxanthin and lutein have little to no influence on the progression of AMD. In general, there remains insufficient evidence to assess the effectiveness of dietary or supplemental zeaxanthin or lutein in treatment or prevention of early AMD.