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XEN103

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564994

CAS#: 840489-44-3

Description: XEN103 is a potent and selective Stearoyl-CoA Desaturase-1 inhibitor.


Price and Availability

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XEN103 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564994
Name: XEN103
CAS#: 840489-44-3
Chemical Formula: C22H23F4N5O2
Exact Mass: 465.1788
Molecular Weight: 465.45
Elemental Analysis: C, 56.77; H, 4.98; F, 16.33; N, 15.05; O, 6.87


Synonym: Xenon 45; XEN103; XEN-103; XEN 103

IUPAC/Chemical Name: N-(2-Cyclopropylethyl)-6-[4-[5-fluoro-2-(trifluoromethyl)benzoyl]piperazin-1-yl]pyridazine-3-carboxamide

InChi Key: QMZSSLLJQUFMHM-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H23F4N5O2/c23-15-3-4-17(22(24,25)26)16(13-15)21(33)31-11-9-30(10-12-31)19-6-5-18(28-29-19)20(32)27-8-7-14-1-2-14/h3-6,13-14H,1-2,7-12H2,(H,27,32)

SMILES Code: O=C(C1=NN=C(N2CCN(C(C3=CC(F)=CC=C3C(F)(F)F)=O)CC2)C=C1)NCCC4CC4


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300


References

1: Zhang Z, Sun S, Kodumuru V, Hou D, Liu S, Chakka N, Sviridov S, Chowdhury S, McLaren DG, Ratkay LG, Khakh K, Cheng X, Gschwend HW, Kamboj R, Fu J, Winther MD. Discovery of piperazin-1-ylpyridazine-based potent and selective stearoyl-CoA desaturase-1 inhibitors for the treatment of obesity and metabolic syndrome. J Med Chem. 2013 Jan 24;56(2):568-83. doi: 10.1021/jm301661h. Epub 2013 Jan 7. PubMed PMID: 23245208.