WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 564946
Description: JBIR-59 is a natural radical scavenger which inhibits L-glutamate toxicity in neuronal hybridoma N18-RE-105 cells.
MedKoo Cat#: 564946
Chemical Formula: C23H28O7
Exact Mass: 416.1835
Molecular Weight: 416.47
Elemental Analysis: C, 66.33; H, 6.78; O, 26.89
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: JBIR59; JBIR 59; JBIR-59
IUPAC/Chemical Name: (4R,4aR,5aS,9aR,9bR,Z)-4,4a,6-Trihydroxy-9-((2E,4E)-1-hydroxyhexa-2,4-dien-1-ylidene)-3,4,5a,7,9b-pentamethyl-4a,9,9a,9b-tetrahydrodibenzo[b,d]furan-1,8(4H,5aH)-dione
InChi Key: PKQREEHLUHFKNJ-YJYGGFIMSA-N
InChi Code: InChI=1S/C23H28O7/c1-7-8-9-10-14(24)16-17(26)13(3)19(27)21(5)18(16)20(4)15(25)11-12(2)22(6,28)23(20,29)30-21/h7-11,18,24,27-29H,1-6H3/b8-7+,10-9+,16-14+/t18-,20+,21+,22-,23-/m1/s1
SMILES Code: O=C1C=C(C)[C@@](C)(O)[C@]2(O)O[C@@](C(O)=C(C)C(/C3=C(O)/C=C/C=C/C)=O)(C)[C@@]3([H])[C@@]21C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 416.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Ueda JY, Hashimoto J, Inaba S, Takagi M, Shin-ya K. JBIR-59, a new sorbicillinoid, from a marine-derived fungus Penicillium citrinum SpI080624G1f01. J Antibiot (Tokyo). 2010 Apr;63(4):203-5. doi: 10.1038/ja.2010.19. Epub 2010 Mar 5. PubMed PMID: 20203701.