WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 581739
CAS#: 32040-45-2
Description: C10Dichol inhibited tremor induced by oxotremorine, nicotine and physostigmine and afforded partial protection from physostigmine-induced mortality in mice. In non-paralysing doses, C10Dichol antagonized the neuromuscular effects of oxotremorine, nicotine and physostigmine.
MedKoo Cat#: 581739
Name: C10-Dichol
CAS#: 32040-45-2
Chemical Formula: C18H42N2O22+
Exact Mass: 318.3235
Molecular Weight: 318.54
Elemental Analysis: C, 67.87; H, 13.29; N, 8.79; O, 10.05
This product is not in stock, which may be available by custom synthesis.
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Synonym: C10-Dichol; C10 Dichol; C10Dichol; C10-Dichol dibromide.
IUPAC/Chemical Name: 1,10-Decanediaminium, N,N'-bis(2-hydroxyethyl)-N,N,N',N'-tetramethyl-
InChi Key: GYPLOIGEEGQIPE-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H42N2O2/c1-19(2,15-17-21)13-11-9-7-5-6-8-10-12-14-20(3,4)16-18-22/h21-22H,5-18H2,1-4H3/q+2
SMILES Code: C[N+](C)(CCO)CCCCCCCCCC[N+](C)(CCO)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 318.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Das M, Ganguly DK, Vedasiromoni JR. Anti-tremor action of C10Dichol, a peripheral acetylcholine synthesis inhibitor. Br J Pharmacol. 1980;71(1):349-53. PubMed PMID: 6258692; PubMed Central PMCID: PMC2044434.
