WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 584797
Description: N 1518 has alpha, beta-adrenergic blocking, antihypertensive and vasodilating properties.
MedKoo Cat#: 584797
Name: N 1518
Chemical Formula: C22H26N2O5
Exact Mass: 398.1842
Molecular Weight: 398.459
Elemental Analysis: C, 66.32; H, 6.58; N, 7.03; O, 20.08
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Synonym: N 1518; N1518; N-1518
IUPAC/Chemical Name: 1(2H)-Isoquinolinone, 4-(2-hydroxy-3-((2-(2-methoxyphenoxy)-1-methylethyl)amino)propoxy)-
InChi Key: BZAQSBHYQKDSGT-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H26N2O5/c1-15(13-28-20-10-6-5-9-19(20)27-2)23-11-16(25)14-29-21-12-24-22(26)18-8-4-3-7-17(18)21/h3-10,12,15-16,23,25H,11,13-14H2,1-2H3,(H,24,26)
SMILES Code: O=C1NC=C(OCC(O)CNC(C)COC2=CC=CC=C2OC)C3=C1C=CC=C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 398.459 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Sugai T. [Pharmacological properties of (+/-)-4-[2-hydroxy-3-(3-(2-methoxyphenoxy)-2-propylamino)propoxy]-1(2H) -isoquinolinone (N-1518), a new combined alpha- and beta-adrenoceptor blocking drug]. Nihon Yakurigaku Zasshi. 1990 Sep;96(3):117-27. Japanese. PubMed PMID: 1980255.