EMBL
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564833

CAS#: 445222-91-3

Description: EMBL is an inhibitor of MuRF1, attenuating skeletal muscle atrophy and dysfunction in cardiac cachexia.


Chemical Structure

img
EMBL
CAS# 445222-91-3

Theoretical Analysis

MedKoo Cat#: 564833
Name: EMBL
CAS#: 445222-91-3
Chemical Formula: C18H15N3O3
Exact Mass: 321.11
Molecular Weight: 321.340
Elemental Analysis: C, 67.28; H, 4.71; N, 13.08; O, 14.94

Price and Availability

Size Price Availability Quantity
5mg USD 530 2 Weeks
10mg USD 850 2 Weeks
25mg USD 1450 2 Weeks
50mg USD 2250 2 Weeks
100mg USD 3850 2 Weeks
Bulk inquiry

Synonym: CID-704946; CID704946; CID 704946; EMBL; MuRF1-IN-1;

IUPAC/Chemical Name: (4R)-2-Amino-1'-methyl-2',5-dioxospiro[7,8-dihydro-6H-chromene-4,3'-indole]-3-carbonitrile

InChi Key: VXTHFLXWLSPJSP-GOSISDBHSA-N

InChi Code: InChI=1S/C18H15N3O3/c1-21-12-6-3-2-5-10(12)18(17(21)23)11(9-19)16(20)24-14-8-4-7-13(22)15(14)18/h2-3,5-6H,4,7-8,20H2,1H3/t18-/m1/s1

SMILES Code: N#CC1=C(N)OC2=C(C(CCC2)=O)[C@]13C(N(C)C4=C3C=CC=C4)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Soluble in DMSO 0.0 100.00

Preparing Stock Solutions

The following data is based on the product molecular weight 321.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x