M 16287

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MedKoo CAT#: 584781

CAS#: 128851-55-8

Description: M 16287 is a potent aldose reductase inhibitor.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-11. Prices are subject to change without notice.

M 16287 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 584781
Name: M 16287
CAS#: 128851-55-8
Chemical Formula: C11H7ClN2O5S
Exact Mass: 313.9764
Molecular Weight: 314.696
Elemental Analysis: C, 41.98; H, 2.24; Cl, 11.26; N, 8.90; O, 25.42; S, 10.19

Synonym: M 16287; M16287; M-16287

IUPAC/Chemical Name: 2,4-Imidazolidinedione, 1-((3-chloro-2-benzofuranyl)sulfonyl)-


InChi Code: InChI=1S/C11H7ClN2O5S/c12-9-6-3-1-2-4-7(6)19-10(9)20(17,18)14-5-8(15)13-11(14)16/h1-4H,5H2,(H,13,15,16)

SMILES Code: O=C1NC(CN1S(=O)(C2=C(Cl)C3=CC=CC=C3O2)=O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Miwa I, Chen AS, Taguchi T. Glyceraldehyde is present in rat lens and its level is increased in diabetes mellitus. Ophthalmic Res. 2009;41(2):98-101. doi: 10.1159/000187626. Epub 2008 Dec 20. PubMed PMID: 19122471.

2: Kato K, Nakayama K, Ohta M, Murakami N, Murakami K, Mizota M, Miwa I, Okuda J. Effects of novel aldose reductase inhibitors, M16209 and M16287, on streptozotocin-induced diabetic neuropathy in rats. Eur J Pharmacol. 1991 Feb 7;193(2):185-91. PubMed PMID: 1828768.

3: Kato K, Nakayama K, Mizota M, Miwa I, Okuda J. Properties of novel aldose reductase inhibitors, M16209 and M16287, in comparison with known inhibitors, ONO-2235 and sorbinil. Chem Pharm Bull (Tokyo). 1991 Jun;39(6):1540-5. PubMed PMID: 1934175.

4: Kato K, Nakayama K, Ohta M, Murakami N, Murakami K, Mizota M, Miwa I, Okuda J. Effects of novel hydantoin derivatives with aldose reductase inhibiting activity on galactose-induced cataract in rats. Jpn J Pharmacol. 1990 Dec;54(4):355-64. PubMed PMID: 2128352.