UK-59811 HCl

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564807


Description: UK-59811 HCl is a calcium channel blocker which inhibits CaVAb and binds at the outer, lipid-facing surface of the pore at the interface between two CaVAb subunits.

Chemical Structure

UK-59811 HCl

Theoretical Analysis

MedKoo Cat#: 564807
Name: UK-59811 HCl
Chemical Formula: C22H30BrClN2O5
Exact Mass:
Molecular Weight: 517.85
Elemental Analysis: C, 51.03; H, 5.84; Br, 15.43; Cl, 6.85; N, 5.41; O, 15.45

Price and Availability

Size Price Availability Quantity
5.0mg USD 280.0 2 Weeks
25.0mg USD 750.0 2 Weeks
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Synonym: UK59811 HCl; UK 59811 HCl; UK-59811 HCl; UK-59811 hydrochloride

IUPAC/Chemical Name: 3-Ethyl 5-methyl 4-(2-bromophenyl)-2-((2-(dimethylamino)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride


InChi Code: InChI=1S/C22H29BrN2O5.ClH/c1-6-30-22(27)20-17(13-29-12-11-25(3)4)24-14(2)18(21(26)28-5)19(20)15-9-7-8-10-16(15)23;/h7-10,19,24H,6,11-13H2,1-5H3;1H


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 517.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Tang L, Gamal El-Din TM, Swanson TM, Pryde DC, Scheuer T, Zheng N, Catterall WA. Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature. 2016 Sep 1;537(7618):117-121. doi: 10.1038/nature19102. Epub 2016 Aug 24. PubMed PMID: 27556947; PubMed Central PMCID: PMC5161592.