Dab-boro-Nle

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564783

CAS#: NONE

Description: Dab-boro-Nle is a selective and potent DPP7 inhibitor with a DPP7 IC50 value of 480 pM.


Price and Availability

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Dab-boro-Nle is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564783
Name: Dab-boro-Nle
CAS#: NONE
Chemical Formula: C9H22BN3O3
Exact Mass: 231.1754
Molecular Weight: 231.1
Elemental Analysis: C, 46.78; H, 9.60; B, 4.68; N, 18.18; O, 20.77


Synonym: Dab-boro-Nle; DabboroNle; Dab boro Nle

IUPAC/Chemical Name: ((R)-1-((S)-2,4-Diaminobutanamido)pentyl)boronic acid

InChi Key: JAXKDVVQQUKJKR-YUMQZZPRSA-N

InChi Code: InChI=1S/C9H22BN3O3/c1-2-3-4-8(10(15)16)13-9(14)7(12)5-6-11/h7-8,15-16H,2-6,11-12H2,1H3,(H,13,14)/t7-,8-/m0/s1

SMILES Code: CCCC[C@@H](B(O)O)NC([C@@H](N)CCN)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300


References

1: Shreder KR, Wong MS, Corral S, Yu Z, Winn DT, Wu M, Hu Y, Nomanbhoy T, Alemayehu S, Fuller SR, Rosenblum JS, Kozarich JW. Boro-norleucine as a P1 residue for the design of selective and potent DPP7 inhibitors. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4256-60. PubMed PMID: 16084722.