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MedKoo CAT#: 564777

CAS#: 896683-84-4 (racemate)

Description: BC-1471 is a selective antagonist of deubiquitinase STAM-binding protein (STAMBP) which decreases NALP7 protein levels and suppresses IL-1β release after TLR agonism.

Price and Availability

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Pricing updated 2020-10-20. Prices are subject to change without notice.

BC-1471 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 564777
Name: BC-1471
CAS#: 896683-84-4 (racemate)
Chemical Formula: C27H32N4O4S
Exact Mass: 508.2144
Molecular Weight: 508.64
Elemental Analysis: C, 63.76; H, 6.34; N, 11.02; O, 12.58; S, 6.30

Related CAS #: 896683-84-4 (racemate)    

Synonym: BC1471; BC 1471; BC-1471

IUPAC/Chemical Name: (R)-2-((6-Morpholino-4-oxo-3-phenethyl-3,4-dihydroquinazolin-2-yl)thio)-N-((tetrahydrofuran-2-yl)methyl)acetamide


InChi Code: InChI=1S/C27H32N4O4S/c32-25(28-18-22-7-4-14-35-22)19-36-27-29-24-9-8-21(30-12-15-34-16-13-30)17-23(24)26(33)31(27)11-10-20-5-2-1-3-6-20/h1-3,5-6,8-9,17,22H,4,7,10-16,18-19H2,(H,28,32)/t22-/m1/s1


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Bednash JS, Weathington N, Londino J, Rojas M, Gulick DL, Fort R, Han S, McKelvey AC, Chen BB, Mallampalli RK. Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity. Nat Commun. 2017 May 11;8:15203. doi: 10.1038/ncomms15203. PubMed PMID: 28492230; PubMed Central PMCID: PMC5437278.