VH 032 Linker 3
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 471017

CAS#: Unknown

Description: VH 032 Linker 3 is a derivative of the proteolysis-targeting chimera technology (PROTAC) for PROTAC research and development; by incorporating an E3 ligase ligand and a short alkyl linker, it is ready for conjugation to a target protein ligand.


Price and Availability

Size
Price

10mg
USD 250
Size
Price

25mg
USD 420
Size
Price

VH 032 Linker 3, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 471017
Name: VH 032 Linker 3
CAS#: Unknown
Chemical Formula: C27H40ClN5O4S
Exact Mass:
Molecular Weight: 566.158
Elemental Analysis: 57.28; H, 7.12; Cl, 6.26; N, 12.37; O, 11.30; S, 5.66


Synonym: VH 032 Linker 3, VH032 Linker 3; VH-032 Linker 3

IUPAC/Chemical Name: (2S,4R)-1-((S)-2-(5-aminopentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

InChi Key: HJICCZROGLAHNB-BIBCNAKVSA-N

InChi Code: InChI=1S/C27H39N5O4S.ClH/c1-17-23(37-16-30-17)19-10-8-18(9-11-19)14-29-25(35)21-13-20(33)15-32(21)26(36)24(27(2,3)4)31-22(34)7-5-6-12-28;/h8-11,16,20-21,24,33H,5-7,12-15,28H2,1-4H3,(H,29,35)(H,31,34);1H/t20-,21+,24-;/m1./s1

SMILES Code: O=C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)[C@H](C(C)(C)C)NC(CCCCN)=O.Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300


References

1. Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID: 28302825