WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 573291
CAS#: 689-13-4 (free)
Description: Hadacidin is an inhibitor of AMP synthesis. Hadacidin and hadacidin analogues have anticancer activity and activity against adenylosuccinate synthetase.
MedKoo Cat#: 573291
Name: Hadacidin
CAS#: 689-13-4 (free)
Chemical Formula: C3H5NO4
Exact Mass: 119.0219
Molecular Weight: 119.08
Elemental Analysis: C, 30.26; H, 4.23; N, 11.76; O, 53.74
Related CAS #: 689-13-4 (free); 2618-22-6 (sodium)
Synonym: Asymmetrin, Hadacidin, Hadacidine, Hadacin,
IUPAC/Chemical Name: Glycine, N-formyl-N-hydroxy-
InChi Key: URJHVPKUWOUENU-UHFFFAOYSA-N
InChi Code: 1S/C3H5NO4/c5-2-4(8)1-3(6)7/h2,8H,1H2,(H,6,7)
SMILES Code: C(C(=O)O)N(C=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 119.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Tibrewal N, Elliott GI. Evaluation of hadacidin analogues. Bioorg Med Chem Lett. 2011 Jan 1;21(1):517-9. doi: 10.1016/j.bmcl.2010.10.088. Epub 2010 Oct 30. PubMed PMID: 21129960.
2: SHIGEURA HT, GORDON CN. The mechanism of action of hadacidin. J Biol Chem. 1962 Jun;237:1937-40. PubMed PMID: 13911879.
