Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg

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MedKoo CAT#: 530799

CAS#: 118675-77-7

Description: Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is a protein kinase C substrate.


Price and Availability

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Pricing updated 2020-10-25. Prices are subject to change without notice.

Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 530799
Name: Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg
CAS#: 118675-77-7
Chemical Formula: C56H110N22O14
Exact Mass: 1314.8572
Molecular Weight: 1315.636
Elemental Analysis: C, 51.12; H, 8.43; N, 23.42; O, 17.02


Synonym: Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg

IUPAC/Chemical Name: L-Arginine, N2-(N2-(N2-(N-(N-(N2-(N-(N2-(N-(N2-L-lysyl-L-arginyl)-L-alanyl)-L-lysyl)-L-alanyl)-L-lysyl)-L-threonyl)-L-threonyl)-L-lysyl)-L-lysyl)-

InChi Key: VBMOHECZZWVLFJ-GXTUVTBFSA-N

InChi Code: InChI=1S/C56H110N22O14/c1-31(70-48(85)40(22-15-29-67-55(63)64)73-46(83)35(62)17-5-10-24-57)44(81)71-36(18-6-11-25-58)47(84)69-32(2)45(82)72-39(21-9-14-28-61)51(88)77-43(34(4)80)53(90)78-42(33(3)79)52(89)75-38(20-8-13-27-60)49(86)74-37(19-7-12-26-59)50(87)76-41(54(91)92)23-16-30-68-56(65)66/h31-43,79-80H,5-30,57-62H2,1-4H3,(H,69,84)(H,70,85)(H,71,81)(H,72,82)(H,73,83)(H,74,86)(H,75,89)(H,76,87)(H,77,88)(H,78,90)(H,91,92)(H4,63,64,67)(H4,65,66,68)/t31-,32-,33+,34+,35-,36-,37-,38-,39-,40-,41-,42-,43-/m0/s1

SMILES Code: N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@H]([C@H](O)C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Tu WZ, Li B, Huang B, Wang Y, Liu XD, Guan H, Zhang SM, Tang Y, Rang WQ, Zhou PK. γH2AX foci formation in the absence of DNA damage: mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway. FEBS Lett. 2013 Nov 1;587(21):3437-43. doi: 10.1016/j.febslet.2013.08.028. Epub 2013 Sep 8. PubMed PMID: 24021642.

2: Sakata K, Matsumoto Y, Tauchi H, Satoh M, Oouchi A, Nagakura H, Koito K, Hosoi Y, Suzuki N, Komatsu K, Hareyama M. Expression of genes involved in repair of DNA double-strand breaks in normal and tumor tissues. Int J Radiat Oncol Biol Phys. 2001 Jan 1;49(1):161-7. PubMed PMID: 11163510.

3: Grode SH, Strother DS, Runge TA, Dobrowolski PJ. Hydrogen fluoride catalyzed migration of side chain protecting groups onto Fmoc during solid phase peptide synthesis. Characterization by CF-FAB analysis of carboxypeptidase digestions and NMR spectroscopy. Int J Pept Protein Res. 1992 Dec;40(6):538-45. PubMed PMID: 1286938.