Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg

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MedKoo CAT#: 530799

CAS#: 118675-77-7

Description: Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is a protein kinase C substrate.


Chemical Structure

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Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg
CAS# 118675-77-7

Theoretical Analysis

MedKoo Cat#: 530799
Name: Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg
CAS#: 118675-77-7
Chemical Formula: C56H110N22O14
Exact Mass: 1,314.86
Molecular Weight: 1,315.636
Elemental Analysis: C, 51.12; H, 8.43; N, 23.42; O, 17.02

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg

IUPAC/Chemical Name: L-Arginine, N2-(N2-(N2-(N-(N-(N2-(N-(N2-(N-(N2-L-lysyl-L-arginyl)-L-alanyl)-L-lysyl)-L-alanyl)-L-lysyl)-L-threonyl)-L-threonyl)-L-lysyl)-L-lysyl)-

InChi Key: VBMOHECZZWVLFJ-GXTUVTBFSA-N

InChi Code: InChI=1S/C56H110N22O14/c1-31(70-48(85)40(22-15-29-67-55(63)64)73-46(83)35(62)17-5-10-24-57)44(81)71-36(18-6-11-25-58)47(84)69-32(2)45(82)72-39(21-9-14-28-61)51(88)77-43(34(4)80)53(90)78-42(33(3)79)52(89)75-38(20-8-13-27-60)49(86)74-37(19-7-12-26-59)50(87)76-41(54(91)92)23-16-30-68-56(65)66/h31-43,79-80H,5-30,57-62H2,1-4H3,(H,69,84)(H,70,85)(H,71,81)(H,72,82)(H,73,83)(H,74,86)(H,75,89)(H,76,87)(H,77,88)(H,78,90)(H,91,92)(H4,63,64,67)(H4,65,66,68)/t31-,32-,33+,34+,35-,36-,37-,38-,39-,40-,41-,42-,43-/m0/s1

SMILES Code: N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@H]([C@H](O)C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 1,315.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Tu WZ, Li B, Huang B, Wang Y, Liu XD, Guan H, Zhang SM, Tang Y, Rang WQ, Zhou PK. γH2AX foci formation in the absence of DNA damage: mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway. FEBS Lett. 2013 Nov 1;587(21):3437-43. doi: 10.1016/j.febslet.2013.08.028. Epub 2013 Sep 8. PubMed PMID: 24021642.

2: Sakata K, Matsumoto Y, Tauchi H, Satoh M, Oouchi A, Nagakura H, Koito K, Hosoi Y, Suzuki N, Komatsu K, Hareyama M. Expression of genes involved in repair of DNA double-strand breaks in normal and tumor tissues. Int J Radiat Oncol Biol Phys. 2001 Jan 1;49(1):161-7. PubMed PMID: 11163510.

3: Grode SH, Strother DS, Runge TA, Dobrowolski PJ. Hydrogen fluoride catalyzed migration of side chain protecting groups onto Fmoc during solid phase peptide synthesis. Characterization by CF-FAB analysis of carboxypeptidase digestions and NMR spectroscopy. Int J Pept Protein Res. 1992 Dec;40(6):538-45. PubMed PMID: 1286938.