Lysine amidotrizoate

Orders received during 11/25~11/29 will be shipped in 11/30/2020 due to Thanksgiving holiday.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530765

CAS#: 77035-55-3

Description: Lysine amidotrizoate is a bioactive chemical.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-11-29. Prices are subject to change without notice.

Lysine amidotrizoate is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 530765
Name: Lysine amidotrizoate
CAS#: 77035-55-3
Chemical Formula: C17H23I3N4O6
Exact Mass: 759.8752
Molecular Weight: 760.1064
Elemental Analysis: C, 26.86; H, 3.05; I, 50.09; N, 7.37; O, 12.63


Synonym: Lysine amidotrizoate

IUPAC/Chemical Name: L-Lysine, mono(3,5-bis(acetylamino)-2,4,6-triiodobenzoate)

InChi Key: PGWLUYCTYOGUBP-ZSCHJXSPSA-N

InChi Code: InChI=1S/C11H9I3N2O4.C6H14N2O2/c1-3(17)15-9-6(12)5(11(19)20)7(13)10(8(9)14)16-4(2)18;7-4-2-1-3-5(8)6(9)10/h1-2H3,(H,15,17)(H,16,18)(H,19,20);5H,1-4,7-8H2,(H,9,10)/t;5-/m.0/s1

SMILES Code: N[C@@H](CCCCN)C(O)=O.O=C(O)C1=C(I)C(NC(C)=O)=C(I)C(NC(C)=O)=C1I


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

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2: Golder W, Dietz G, Rittinghaus K, Weinberg P, Jarosch M. Absorption of L-lysine diatrizoate from the gastrointestinal tract: the effect of surgery, inflammation, and neoplasia. Int J Colorectal Dis. 2003 Sep;18(5):428-32. Epub 2003 Apr 2. PubMed PMID: 12677458.

3: Golder W, Dietz G, Rittinghaus K, Weinberg P, Jarosch M. [Absorption of L-lysine diatrizoate from the gastrointestinal tract: the influence of surgery, inflammation and neoplasia]. Rofo. 2003 Mar;175(3):401-5. German. PubMed PMID: 12635018.

4: Moll R, Mittelkötter U, Reith HB, Schindler G, Thiede A. [Which imaging in case of sigmoid diverticulitis? The value of ultrasound (Conventional B-mode in combination with hydrocolonsonography and colour flow Doppler) in comparison to the well-established modalities like contrast enema and helical computertomography]. Zentralbl Chir. 2002 Apr;127(4):297-301. German. PubMed PMID: 12085279.

5: Cipolla P, Castano M, Kirchin MA, de Haën C, Tirone P. Effects of iodinated contrast media on pulmonary airway resistance in anesthetized guinea pigs. Acad Radiol. 1995 Apr;2(4):306-12. PubMed PMID: 9419567.

6: Grabowski EF, Rodriguez M, McDonnell SL. Platelet adhesion/aggregation in an in vitro model of coronary artery stenosis. Cathet Cardiovasc Diagn. 1993 Jan;28(1):65-71. PubMed PMID: 8416335.

7: Stäbler A, Fink U, Siuda S, Neville S. [Inter-individual testing of water-soluble oral contrast media with reference to their diagnostic value, side effects and taste]. Rontgenblatter. 1989 May;42(5):224-7. German. PubMed PMID: 2502828.

8: Kinawi A, Hecker A, Hassan MH. [Determination of the binding of 3,5-bis(acetamido)-2,4,6-triiodobenzoic acid and some of its salts to human serum albumin using the ultrafiltration flat chamber method]. Arzneimittelforschung. 1984;34(7):819-21. German. PubMed PMID: 6541917.

9: Wolpers HG, Baller D, Ensink FB, Hoeft A, Korb H, Hellige G. [Effects of radiographic contrast media on cellular electrophysiology in the beating heart (author's transl)]. Z Kardiol. 1982 Jan;71(2):82-6. German. PubMed PMID: 6803468.

10: Vorpahl WD. [The roentgen-optical and clinical properties of peritrast]. Med Welt. 1981 Nov 20;32(47):1790-3. German. PubMed PMID: 6796800.

11: Hahn N, Raqué B, Schuppert J, Schmidt I, Mählmann J, Logemann N, Potthoff E, Pantenburg R, Stiemert D, Siering T, Steinijans V, Diletti E, Felix R. Contrast media-induced side effects on excitation and conduction of electrical activity in the heart on intracardiac application. Investigations in anaesthetized dogs. Eur J Radiol. 1981 Nov;1(4):270-7. PubMed PMID: 7346272.

12: Schilling T, Tardos S. [Experience in endoscopic retrograde cholangio-pancreaticography with Peritrast 400 comp (author's transl)]. Rontgenblatter. 1980 Aug;33(8):410-3. German. PubMed PMID: 6773137.

13: Würdinger H. [Excretory behavior of L-lysine amidotrizoate]. Med Welt. 1979 Jun 29;30(26):1011-2. German. PubMed PMID: 459833.

14: Beythien RD, Sieberns H. [Clinical experiences using L-lysine amidotrizoate in vascular diagnostics]. Med Welt. 1978 Jun 9;29(23):973-5. German. PubMed PMID: 661545.

15: Strosche H, Labitzke R, Draese K. [Clinical experience with a new roentgen contrast medium for special pre-, intra-, and postoperative diagnosis of biliary tract diseases]. Med Welt. 1976 Nov 12;27(46):2244-7. German. PubMed PMID: 1004165.

16: Wehling H. [A new contrast medium (author's transl)]. Radiologe. 1975 Sep;15(9):373-6. German. PubMed PMID: 1188093.