Lysine monohydrate

We are open as normal in holiday season. We are closed in Dec 24, Dec 25 and Jan 1.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530758

CAS#: 39665-12-8

Description: Lysine monohydrate is a bioactive chemical.


Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-12-05. Prices are subject to change without notice.

Lysine monohydrate is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 530758
Name: Lysine monohydrate
CAS#: 39665-12-8
Chemical Formula: C6H16N2O3
Exact Mass: 164.1161
Molecular Weight: 164.205
Elemental Analysis: C, 43.89; H, 9.82; N, 17.06; O, 29.23


Synonym: Lysine monohydrate

IUPAC/Chemical Name: l-Lysine, monohydrate

InChi Key: HZRUTVAFDWTKGD-JEDNCBNOSA-N

InChi Code: InChI=1S/C6H14N2O2.H2O/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H2/t5-;/m0./s1

SMILES Code: N[C@@H](CCCCN)C(O)=O.[H]O[H]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Rimer JD, Kolbach-Mandel AM, Ward MD, Wesson JA. The role of macromolecules in the formation of kidney stones. Urolithiasis. 2017 Feb;45(1):57-74. doi: 10.1007/s00240-016-0948-8. Epub 2016 Dec 2. Review. PubMed PMID: 27913854; PubMed Central PMCID: PMC5253101.

2: Panpisut P, Liaqat S, Zacharaki E, Xia W, Petridis H, Young AM. Dental Composites with Calcium / Strontium Phosphates and Polylysine. PLoS One. 2016 Oct 11;11(10):e0164653. doi: 10.1371/journal.pone.0164653. eCollection 2016. PubMed PMID: 27727330; PubMed Central PMCID: PMC5058497.

3: Wang L, Zhang GH, Wang XQ, Zhu LY, Xu D. Guanidine-phosphate non-covalent interaction in LAP crystal growth solution evidenced from spectroscopy studies. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Sep 5;148:12-7. doi: 10.1016/j.saa.2015.03.124. Epub 2015 Apr 4. PubMed PMID: 25863455.

4: Farmanesh S, Chung J, Sosa RD, Kwak JH, Karande P, Rimer JD. Natural promoters of calcium oxalate monohydrate crystallization. J Am Chem Soc. 2014 Sep 10;136(36):12648-57. doi: 10.1021/ja505402r. Epub 2014 Aug 27. PubMed PMID: 25119124.

5: Mahadevan M, Magesh M, Ramachandran K, Anandan P, Arivanandhan M, Hayakawa Y. Synthesis, growth, crystal structure and characterization of a new organic NLO crystal: L-lysine 4-nitrophenolate monohydrate (LLPNP). Spectrochim Acta A Mol Biomol Spectrosc. 2014 Sep 15;130:416-22. doi: 10.1016/j.saa.2014.04.033. Epub 2014 Apr 18. PubMed PMID: 24810028.

6: Albarellos GA, Montoya L, Quaine PC, Landoni MF. Pharmacokinetics and bioavailability of a long-acting formulation of cephalexin after intramuscular administration to cats. Res Vet Sci. 2011 Aug;91(1):129-31. doi: 10.1016/j.rvsc.2010.08.001. Epub 2010 Aug 25. PubMed PMID: 20800248.

7: Garavaglia ML, Bononi E, Dossena S, Mondini A, Bazzini C, Lanata L, Balsamo R, Bagnasco M, Conese M, Bottà G, Paulmichl M, Meyer G. S-CMC-Lys protective effects on human respiratory cells during oxidative stress. Cell Physiol Biochem. 2008;22(5-6):455-64. doi: 10.1159/000185494. Epub 2008 Dec 9. PubMed PMID: 19088427.

8: Selvaraj M, Thamotharan S, Roy S, Vijayan M. X-ray studies of crystalline complexes involving amino acids and peptides. XLIV. Invariant features of supramolecular association and chiral effects in the complexes of arginine and lysine with tartaric acid. Acta Crystallogr B. 2007 Jun;63(Pt 3):459-68. Epub 2007 May 16. PubMed PMID: 17507759.

9: Bryce DL, Sward GD, Adiga S. Solid-state 35/37Cl NMR spectroscopy of hydrochloride salts of amino acids implicated in chloride ion transport channel selectivity: opportunities at 900 MHz. J Am Chem Soc. 2006 Feb 15;128(6):2121-34. PubMed PMID: 16464115.

10: Guizzardi F, Rodighiero S, Binelli A, Saino S, Bononi E, Dossena S, Garavaglia ML, Bazzini C, Bottà G, Conese M, Daffonchio L, Novellini R, Paulmichl M, Meyer G. S-CMC-Lys-dependent stimulation of electrogenic glutathione secretion by human respiratory epithelium. J Mol Med (Berl). 2006 Jan;84(1):97-107. Epub 2005 Nov 11. PubMed PMID: 16283140.

11: Doi M, Nakamoto Y, Asano A. Cytosine-containing hybrid dipeptides: N-[2-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)propionyl]-L-phenylalanine N-[2-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)propionyl]-L-serine monohydrate and N-[2-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)propionyl]-L-lysine. Acta Crystallogr C. 2005 Oct;61(Pt 10):m577-82. Epub 2005 Sep 10. PubMed PMID: 16210762.

12: Carpagnano GE, Resta O, Foschino-Barbaro MP, Spanevello A, Stefano A, Di Gioia G, Serviddio G, Gramiccioni E. Exhaled Interleukine-6 and 8-isoprostane in chronic obstructive pulmonary disease: effect of carbocysteine lysine salt monohydrate (SCMC-Lys). Eur J Pharmacol. 2004 Nov 28;505(1-3):169-75. PubMed PMID: 15556150.

13: Saraswathi NT, Roy S, Vijayan M. X-ray studies on crystalline complexes involving amino acids and peptides. XLI. Commonalities in aggregation and conformation revealed by the crystal structures of the pimelic acid complexes of L-arginine and DL-lysine. Acta Crystallogr B. 2003 Oct;59(Pt 5):641-6. Epub 2003 Sep 25. PubMed PMID: 14586085.

14: Selvam R, Kalaiselvi P. Oxalate binding proteins in calcium oxalate nephrolithiasis. Urol Res. 2003 Aug;31(4):242-56. Epub 2003 Jul 11. Review. PubMed PMID: 12856168.

15: Brandolini L, Allegretti M, Berdini V, Cervellera MN, Mascagni P, Rinaldi M, Melillo G, Ghezzi P, Mengozzi M, Bertini R. Carbocysteine lysine salt monohydrate (SCMC-LYS) is a selective scavenger of reactive oxygen intermediates (ROIs). Eur Cytokine Netw. 2003 Jan-Mar;14(1):20-6. PubMed PMID: 12799210.

16: Berg EP, Allee GL. Creatine monohydrate supplemented in swine finishing diets and fresh pork quality: I. A controlled laboratory experiment. J Anim Sci. 2001 Dec;79(12):3075-80. PubMed PMID: 11811462.

17: Pinamonti S, Venturoli L, Leis M, Chicca M, Barbieri A, Sostero S, Ravenna F, Daffonchio L, Novellini R, Ciaccia A. Antioxidant activity of carbocysteine lysine salt monohydrate. Panminerva Med. 2001 Sep;43(3):215-20. PubMed PMID: 11579333.

18: Sun C, Grant DJ. Compaction properties of L-lysine salts. Pharm Res. 2001 Mar;18(3):281-6. PubMed PMID: 11442265.

19: Selvam R, Kalaiselvi P. A novel basic protein from human kidney which inhibits calcium oxalate crystal growth. BJU Int. 2000 Jul;86(1):7-13. PubMed PMID: 10886075.

20: Eda S, Sherman IW. The effects of chemical modification on the adhesion of Plasmodium falciparum-infected and uninfected erythrocytes. Parasitology. 1998 Dec;117 ( Pt 6):533-40. PubMed PMID: 9881377.