Lysine dihydrochloride, D-

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MedKoo CAT#: 530751

CAS#: 10303-72-7

Description: Lysine dihydrochloride, D- is a bioactive chemical.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-12-05. Prices are subject to change without notice.

Lysine dihydrochloride, D- is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 530751
Name: Lysine dihydrochloride, D-
CAS#: 10303-72-7
Chemical Formula: C6H16Cl2N2O2
Exact Mass: 218.0589
Molecular Weight: 219.106
Elemental Analysis: C, 32.89; H, 7.36; Cl, 32.36; N, 12.79; O, 14.60

Synonym: Lysine dihydrochloride, D-

IUPAC/Chemical Name: D-Lysine, dihydrochloride


InChi Code: InChI=1S/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/t5-;;/m1../s1

SMILES Code: N[C@H](CCCCN)C(O)=O.[H]Cl.[H]Cl

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Kolodziejczyk-Czepas J, Pasiński B, Ponczek MB, Moniuszko-Szajwaj B, Kowalczyk M, Pecio Ł, Nowak P, Stochmal A. Bufadienolides from Kalanchoe daigremontiana modulate the enzymatic activity of plasmin - In vitro and in silico analyses. Int J Biol Macromol. 2018 Dec;120(Pt B):1591-1600. doi: 10.1016/j.ijbiomac.2018.09.143. Epub 2018 Sep 24. PubMed PMID: 30261260.

2: Gründel A, Pfeiffer M, Jacobs E, Dumke R. Network of Surface-Displayed Glycolytic Enzymes in Mycoplasma pneumoniae and Their Interactions with Human Plasminogen. Infect Immun. 2015 Dec 14;84(3):666-76. doi: 10.1128/IAI.01071-15. PubMed PMID: 26667841; PubMed Central PMCID: PMC4771348.

3: Capulli M, Olstad OK, Onnerfjord P, Tillgren V, Muraca M, Gautvik KM, Heinegård D, Rucci N, Teti A. The C-terminal domain of chondroadherin: a new regulator of osteoclast motility counteracting bone loss. J Bone Miner Res. 2014 Aug;29(8):1833-46. doi: 10.1002/jbmr.2206. PubMed PMID: 24616121.

4: Mendes RS, Von Atzingen M, de Morais ZM, Gonçales AP, Serrano SM, Asega AF, Romero EC, Vasconcellos SA, Nascimento AL. The novel leptospiral surface adhesin Lsa20 binds laminin and human plasminogen and is probably expressed during infection. Infect Immun. 2011 Nov;79(11):4657-67. doi: 10.1128/IAI.05583-11. Epub 2011 Aug 15. PubMed PMID: 21844229; PubMed Central PMCID: PMC3257903.

5: Vieira ML, Atzingen MV, Oliveira TR, Oliveira R, Andrade DM, Vasconcellos SA, Nascimento AL. In vitro identification of novel plasminogen-binding receptors of the pathogen Leptospira interrogans. PLoS One. 2010 Jun 22;5(6):e11259. doi: 10.1371/journal.pone.0011259. PubMed PMID: 20582320; PubMed Central PMCID: PMC2889836.

6: Sikora AG, Gelbard A, Davies MA, Sano D, Ekmekcioglu S, Kwon J, Hailemichael Y, Jayaraman P, Myers JN, Grimm EA, Overwijk WW. Targeted inhibition of inducible nitric oxide synthase inhibits growth of human melanoma in vivo and synergizes with chemotherapy. Clin Cancer Res. 2010 Mar 15;16(6):1834-44. doi: 10.1158/1078-0432.CCR-09-3123. Epub 2010 Mar 9. PubMed PMID: 20215556; PubMed Central PMCID: PMC2858983.

7: Alizadeh H, Neelam S, Niederkorn JY. Role of activated macrophages in Acanthamoeba keratitis. J Parasitol. 2007 Oct;93(5):1114-20. doi: 10.1645/GE-1083R.1. PubMed PMID: 18163346.

8: Coon S, Shao G, Wisel S, Vulaupalli R, Sundaram U. Mechanism of regulation of rabbit intestinal villus cell brush border membrane Na/H exchange by nitric oxide. Am J Physiol Gastrointest Liver Physiol. 2007 Feb;292(2):G475-81. PubMed PMID: 17290013.

9: Bodnárová M, Martásek P, Moroz LL. Calcium/calmodulin-dependent nitric oxide synthase activity in the CNS of Aplysia californica: biochemical characterization and link to cGMP pathways. J Inorg Biochem. 2005 Apr;99(4):922-8. PubMed PMID: 15811509.

10: Xu Z, Park SS, Mueller RA, Bagnell RC, Patterson C, Boysen PG. Adenosine produces nitric oxide and prevents mitochondrial oxidant damage in rat cardiomyocytes. Cardiovasc Res. 2005 Mar 1;65(4):803-12. PubMed PMID: 15721860.

11: Schaefer L, Beck KF, Raslik I, Walpen S, Mihalik D, Micegova M, Macakova K, Schonherr E, Seidler DG, Varga G, Schaefer RM, Kresse H, Pfeilschifter J. Biglycan, a nitric oxide-regulated gene, affects adhesion, growth, and survival of mesangial cells. J Biol Chem. 2003 Jul 11;278(28):26227-37. Epub 2003 Apr 27. PubMed PMID: 12719420.

12: Franco L, Doria D. Nitric oxide enhances prostaglandin production in ethanol-induced gastric mucosal injury in rats. Eur J Pharmacol. 1998 May 8;348(2-3):247-56. PubMed PMID: 9652340.

13: Ginsburg I, Kohen R. Synergistic effects among oxidants, membrane-damaging agents, fatty acids, proteinases, and xenobiotics: killing of epithelial cells and release of arachidonic acid. Inflammation. 1995 Feb;19(1):101-18. PubMed PMID: 7705882.

14: Christodoulides M, Boucher DW. The potency of tissue-type plasminogen activator (TPA) determined with chromogen and clot-lysis assays. Biologicals. 1990 Apr;18(2):103-11. PubMed PMID: 2115789.

15: Higazi AA, Mayer M. Effects of penicillins and 6-aminohexanoic acid on the kinetics of human plasmin. Biochem J. 1989 Jun 1;260(2):609-12. PubMed PMID: 2527494; PubMed Central PMCID: PMC1138714.

16: Simpson GM, Khajawall AM. Urinary acidifiers in phencyclidine detoxification. Hillside J Clin Psychiatry. 1983;5(2):161-8. PubMed PMID: 6423507.