WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564692


Description: E-37P is a potent antiproliferative agent.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 564692
Name: E-37P
Chemical Formula: C39H53N3O4
Exact Mass: 627.40
Molecular Weight: 627.870
Elemental Analysis: C, 74.61; H, 8.51; N, 6.69; O, 10.19

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: E37P; E 37P; E-37P

IUPAC/Chemical Name: 1-((2-Naphthoyl)-L-prolyl)-4-((2S,3S,5S,8R,9S,10S,13S,14S,17S)-3,17-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-2-yl)piperazine


InChi Code: InChI=1S/C39H53N3O4/c1-38-16-15-31-29(30(38)13-14-35(38)44)12-11-28-23-34(43)33(24-39(28,31)2)40-18-20-41(21-19-40)37(46)32-8-5-17-42(32)36(45)27-10-9-25-6-3-4-7-26(25)22-27/h3-4,6-7,9-10,22,28-35,43-44H,5,8,11-21,23-24H2,1-2H3/t28-,29-,30-,31-,32-,33-,34-,35-,38-,39-/m0/s1

SMILES Code: C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CC[C@@]4([H])C[C@H](O)[C@@H](N5CCN(C([C@H]6N(C(C7=CC=C8C=CC=CC8=C7)=O)CCC6)=O)CC5)C[C@]4(C)[C@@]3([H])CC2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 627.870000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Ayan D, Maltais R, Hospital A, Poirier D. Chemical synthesis, cytotoxicity, selectivity and bioavailability of 5α-androstane-3α,17β-diol derivatives. Bioorg Med Chem. 2014 Nov 1;22(21):5847-59. doi: 10.1016/j.bmc.2014.09.026. Epub 2014 Sep 19. PubMed PMID: 25300820. 2: Roy J, Maltais R, Jegham H, Poirier D. Libraries of 2β-(N-substituted piperazino)-5α-androstane-3α, 17β-diols: chemical synthesis and cytotoxic effects on human leukemia HL-60 cells and on normal lymphocytes. Mol Divers. 2011 May;15(2):317-39. doi: 10.1007/s11030-010-9273-2. Epub 2010 Sep 9. PubMed PMID: 20827507.