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MedKoo CAT#: 564640


Description: D2923 is a selective inhibitor of colony-stimulating factor 1 receptor (CSF1R).

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-06-06. Prices are subject to change without notice.

D2923 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 564640
Name: D2923
Chemical Formula: C31H36Cl2N8O2
Exact Mass: 622.2338
Molecular Weight: 623.58
Elemental Analysis: C, 59.71; H, 5.82; Cl, 11.37; N, 17.97; O, 5.13

Synonym: D-2923; D 2923; D2923

IUPAC/Chemical Name: (S)-3-(2,6-Dichlorophenyl)-7-((3-methyl-4-(4-methylpiperazin-1-yl)phenyl)amino)-1-(1-propionylpyrrolidin-3-yl)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one


InChi Code: InChI=1S/C31H36Cl2N8O2/c1-4-27(42)39-11-10-23(19-39)41-29-21(18-40(31(41)43)28-24(32)6-5-7-25(28)33)17-34-30(36-29)35-22-8-9-26(20(2)16-22)38-14-12-37(3)13-15-38/h5-9,16-17,23H,4,10-15,18-19H2,1-3H3,(H,34,35,36)/t23-/m0/s1

SMILES Code: O=C1N([C@@H]2CN(C(CC)=O)CC2)C3=NC(NC4=CC=C(N5CCN(C)CC5)C(C)=C4)=NC=C3CN1C6=C(Cl)C=CC=C6Cl

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Liu YQ, Wang YN, Lu XY, Tong LJ, Li Y, Zhang T, Xun QJ, Feng F, Chen YZ, Su Y, Shen YY, Chen Y, Geng MY, Ding K, Li YL, Xie H, Ding J. Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R. Acta Pharmacol Sin. 2018 Nov;39(11):1768-1776. doi: 10.1038/s41401-018-0056-0. Epub 2018 Jul 3. PubMed PMID: 29968849; PubMed Central PMCID: PMC6289367.