Vitexin 4"-O-glucoside

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564532

CAS#: 178468-00-3

Description: Vitexin 4"-O-glucoside is a natural inhibitor of ST2 (IL1RL1).


Price and Availability

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Vitexin 4"-O-glucoside is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564532
Name: Vitexin 4"-O-glucoside
CAS#: 178468-00-3
Chemical Formula: C33H40O19
Exact Mass: 740.2164
Molecular Weight: 740.66
Elemental Analysis: C, 53.51; H, 5.44; O, 41.04


Synonym: Vitexin 4"-O-glucoside; Vitexin 4" O glucoside; Vitexin 4" O-glucoside

IUPAC/Chemical Name: 8-[(2S,4S,5S)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,4S,5R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]-5,7-dihydroxy-2-[4-[(2S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one

InChi Key: LJDOSKINEPZMJE-OKNFIAIGSA-N

InChi Code: InChI=1S/C33H40O19/c1-10-21(39)24(42)27(45)32(47-10)52-31-26(44)23(41)17(8-34)50-30(31)20-14(37)6-13(36)19-15(38)7-16(49-29(19)20)11-2-4-12(5-3-11)48-33-28(46)25(43)22(40)18(9-35)51-33/h2-7,10,17-18,21-28,30-37,39-46H,8-9H2,1H3/t10?,17?,18?,21-,22+,23+,24-,25?,26-,27?,28?,30-,31?,32-,33+/m0/s1

SMILES Code: O=C1C=C(C2=CC=C(O[C@@H]3OC(CO)[C@@H](O)C(O)C3O)C=C2)OC4=C1C(O)=CC(O)=C4[C@@H]5OC(CO)[C@@H](O)[C@H](O)C5O[C@@H]6OC(C)[C@H](O)[C@H](O)C6O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Hou K, Chen F, Zu Y, Yang L. Ionic liquids-lithium salts pretreatment followed by ultrasound-assisted extraction of vitexin-4″-O-glucoside, vitexin-2″-O-rhamnoside and vitexin from Phyllostachys edulis leaves. J Chromatogr A. 2016 Jan 29;1431:17-26. doi: 10.1016/j.chroma.2015.12.067. Epub 2015 Dec 30. PubMed PMID: 26763300.

2: Li H, Liu Y, Jin H, Liu S, Fang S, Wang C, Xia C. Separation of vitexin-4″-O-glucoside and vitexin-2″-O-rhamnoside from hawthorn leaves extracts using macroporous resins. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Dec 15;1007:23-9. doi: 10.1016/j.jchromb.2015.10.043. Epub 2015 Oct 30. PubMed PMID: 26562804.

3: Liu R, Cai Z, Xu B. Characterization and quantification of flavonoids and saponins in adzuki bean (Vigna angularis L.) by HPLC-DAD-ESI-MS(n) analysis. Chem Cent J. 2017 Sep 22;11(1):93. doi: 10.1186/s13065-017-0317-x. PubMed PMID: 29086903; PubMed Central PMCID: PMC5610137.

4: Wei W, Ying X, Zhang W, Chen Y, Leng A, Jiang C, Liu J. Effects of vitexin-2"-O-rhamnoside and vitexin-4"-O-glucoside on growth and oxidative stress-induced cell apoptosis of human adipose-derived stem cells. J Pharm Pharmacol. 2014 Jul;66(7):988-97. doi: 10.1111/jphp.12225. Epub 2014 Feb 17. PubMed PMID: 24533889.

5: Cai S, Chen Y, Zhang W, Ying X. Comparative study on the excretion of vitexin-4''-O-glucoside in mice after oral and intravenous administration by using HPLC. Biomed Chromatogr. 2013 Nov;27(11):1375-9. doi: 10.1002/bmc.2931. Epub 2013 Jun 13. PubMed PMID: 23760836.