We are open as normal during COVID-19 pandemic. Order online, same day shipping out.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564488

CAS#: 1021463-02-4

Description: C1A is an inhibitor of HDAC6 which modulates downstream autophagy substrates and leads to growth inhibition of a diverse set of cancer cell lines.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-06-06. Prices are subject to change without notice.

C1A is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 564488
Name: C1A
CAS#: 1021463-02-4
Chemical Formula: C22H25Cl2N3O4S
Exact Mass: 497.0943
Molecular Weight: 498.42
Elemental Analysis: C, 53.02; H, 5.06; Cl, 14.22; N, 8.43; O, 12.84; S, 6.43

Synonym: C1-A; C-1A; C1 A; C 1A; C1A

IUPAC/Chemical Name: (2E,4E)-5-[4-[[[4-[Bis(2-chloroethyl)amino]phenyl]sulfonyl]amino]phenyl]-N-hydroxy-4-methyl-2,4-pentadienamide


InChi Code: InChI=1S/C22H25Cl2N3O4S/c1-17(2-11-22(28)25-29)16-18-3-5-19(6-4-18)26-32(30,31)21-9-7-20(8-10-21)27(14-12-23)15-13-24/h2-11,16,26,29H,12-15H2,1H3,(H,25,28)/b11-2+,17-16+

SMILES Code: O=C(NO)/C=C/C(C)=C/C1=CC=C(NS(=O)(C2=CC=C(N(CCCl)CCCl)C=C2)=O)C=C1

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Kaliszczak M, van Hechanova E, Li Y, Alsadah H, Parzych K, Auner HW, Aboagye EO. The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death. Br J Cancer. 2018 Oct 15. doi: 10.1038/s41416-018-0232-5. [Epub ahead of print] PubMed PMID: 30318510.