WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 581596
CAS#: 25374-67-8
Description: Zygosporin D is one of the cytochalasins was isolated from the culture filtrate of the fungus Metarrhizium anisopliae.
MedKoo Cat#: 581596
Name: Zygosporin D
CAS#: 25374-67-8
Chemical Formula: C28H35NO5
Exact Mass: 465.2515
Molecular Weight: 465.59
Elemental Analysis: C, 72.23; H, 7.58; N, 3.01; O, 17.18
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Synonym: Zygosporin D; Deactylzygosporin A; Zygosporin D.
IUPAC/Chemical Name: (3R,3aS,4S,6S,6aR,7E,10S,12R,13Z,15R,15aS)-3-benzyl-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-3,3a,4,5,6,6a,9,10,12,15-decahydro-1H-cycloundeca[d]isoindole-1,11(2H)-dione
InChi Key: DMUBZPWTFAPROZ-XFFBKQMBSA-N
InChi Code: InChI=1S/C28H35NO5/c1-16-9-8-12-20-24(31)18(3)17(2)23-21(15-19-10-6-5-7-11-19)29-26(33)28(20,23)22(30)13-14-27(4,34)25(16)32/h5-8,10-14,16-17,20-24,30-31,34H,3,9,15H2,1-2,4H3,(H,29,33)/b12-8+,14-13-/t16-,17+,20-,21+,22+,23+,24+,27+,28-/m0/s1
SMILES Code: C1([C@@]23[C@H]([C@@H](Cc4ccccc4)N1)[C@@H](C(=C)[C@H]([C@@H]2C=CC[C@H](C)C([C@](C=C[C@H]3O)(C)O)=O)O)C)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 465.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Li XG, Pan WD, Zhang XJ, Xiao JH. [Antitumor Chemical Entities of Cordyceps taii Mycelia Powder from Guizhou]. Zhong Yao Cai. 2015 Oct;38(10):2083-6. Chinese. PubMed PMID: 27254919.
2: Fujii Y, Tani H, Ichinoe M, Nakajima H. Zygosporin D and two new cytochalasins produced by the fungus Metarrhizium anisopliae. J Nat Prod. 2000 Jan;63(1):132-5. PubMed PMID: 10650095.
3: Betina V, Janstová D, Spisiaková J. Effects of antibiotics on the life cycle of Neurospora crassa. Folia Microbiol (Praha). 1975;20(4):340-5. PubMed PMID: 51812.
4: Aldridge DC, Turner WB. The identity of zygosporin A and cytochalasin D. J Antibiot (Tokyo). 1969 Apr;22(4):170. PubMed PMID: 5800426.
