VH03-linker

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564440

CAS#: 2064292-52-8

Description: VH03-linker is a precursor of VHL ligand for PROTACs.


Price and Availability

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VH03-linker is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564440
Name: VH03-linker
CAS#: 2064292-52-8
Chemical Formula: C32H50ClN5O8S
Exact Mass:
Molecular Weight: 700.29
Elemental Analysis: C, 54.88; H, 7.20; Cl, 5.06; N, 10.00; O, 18.28; S, 4.58


Synonym: VH-03 linker; VH 03 linker; VH03 linker; VH03-linker

IUPAC/Chemical Name: (2S,4R)-1-((S)-17-Amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Hydrochloride

InChi Key: MSKHBFIXTCSMKP-DDLJGEAHSA-N

InChi Code: InChI=1S/C32H49N5O8S.ClH/c1-22-28(46-21-35-22)24-7-5-23(6-8-24)18-34-30(40)26-17-25(38)19-37(26)31(41)29(32(2,3)4)36-27(39)20-45-16-15-44-14-13-43-12-11-42-10-9-33;/h5-8,21,25-26,29,38H,9-20,33H2,1-4H3,(H,34,40)(H,36,39);1H/t25-,26+,29-;/m1./s1

SMILES Code: O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCOCCOCCN)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00