BDZ-h

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564426

CAS#: 1516903-65-3

Description: BDZ-h is a potent inhibitor of both the closed-channel and the open-channel conformations of all four homomeric AMPA receptor channels and two GluA2R containing complex AMPA receptor channels.


Price and Availability

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BDZ-h is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564426
Name: BDZ-h
CAS#: 1516903-65-3
Chemical Formula: C21H21N5O3S
Exact Mass: 423.1365
Molecular Weight: 423.49
Elemental Analysis: C, 59.56; H, 5.00; N, 16.54; O, 11.33; S, 7.57


Synonym: GYKI47654; GYKI 47654; GYKI-47654; BDZh; BDZ h; BDZ-h

IUPAC/Chemical Name: (R)-5-(4-amino-3-methylphenyl)-8-methyl-7-(2-methyl-3-oxo-2,3-dihydro-1,2,4-thiadiazol-5-yl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine

InChi Key: NLWIBQSPHZSWCV-GFCCVEGCSA-N

InChi Code: InChI=1S/C21H21N5O3S/c1-11-6-13(4-5-16(11)22)19-15-9-18-17(28-10-29-18)8-14(15)7-12(2)26(24-19)21-23-20(27)25(3)30-21/h4-6,8-9,12H,7,10,22H2,1-3H3/t12-/m1/s1

SMILES Code: O=C1N(C)SC(N2N=C(C3=CC=C(N)C(C)=C3)C4=CC(OCO5)=C5C=C4C[C@H]2C)=N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00