WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581571

CAS#: 38753-76-3

Description: 7α-Thio Spironolactone is a Spironolactone (sc-204294) metabolite.

Chemical Structure

CAS# 38753-76-3

Theoretical Analysis

MedKoo Cat#: 581571
Name: 7alpha-Thiospironolactone
CAS#: 38753-76-3
Chemical Formula: C22H30O3S
Exact Mass: 374.1916
Molecular Weight: 374.539
Elemental Analysis: C, 70.55; H, 8.07; O, 12.81; S, 8.56

Price and Availability

Size Price Availability Quantity
5.0mg USD 310.0 2 Weeks
10.0mg USD 530.0 2 Weeks
25.0mg USD 1030.0 2 Weeks
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Synonym: 7alpha-Thiospironolactone; Deacetylspironolactone;

IUPAC/Chemical Name: (7R,8R,9S,10S,13R,14S,17R)-7-mercapto-10,13-dimethyl-1,3',4',6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione


InChi Code: InChI=1S/C22H30O3S/c1-20-7-3-14(23)11-13(20)12-17(26)19-15(20)4-8-21(2)16(19)5-9-22(21)10-6-18(24)25-22/h11,15-17,19,26H,3-10,12H2,1-2H3/t15-,16-,17+,19+,20+,21+,22+/m0/s1

SMILES Code: C1CC(O[C@@]21CC[C@H]1[C@H]3[C@H](CC[C@@]21C)[C@@]1(CCC(C=C1C[C@H]3S)=O)C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 374.539 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: B S, G S, V KR, S G. Microbial synthesis of mammalian metabolites of spironolactone by thermophilic fungus Thermomyces lanuginosus. Steroids. 2018 Aug;136:1-7. doi: 10.1016/j.steroids.2018.05.011. Epub 2018 May 25. PubMed PMID: 29803817.