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MedKoo CAT#: 564380

CAS#: 2222737-15-5

Description: VU6007678 is a muscarinic acetylcholine receptor positive allosteric modulator (PAM).

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-26. Prices are subject to change without notice.

VU6007678 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 564380
Name: VU6007678
CAS#: 2222737-15-5
Chemical Formula: C25H29FN4O3S
Exact Mass: 484.1944
Molecular Weight: 484.59
Elemental Analysis: C, 61.96; H, 6.03; F, 3.92; N, 11.56; O, 9.90; S, 6.62

Synonym: VU-6007678; VU 6007678; VU6007678

IUPAC/Chemical Name: (R)-1-((1H-Indazol-5-yl)sulfonyl)-N-(4-fluoro-2,3-dihydro-1H-inden-1-yl)-N-propylpiperidine-4-carboxamide


InChi Code: InChI=1S/C25H29FN4O3S/c1-2-12-30(24-9-7-20-21(24)4-3-5-22(20)26)25(31)17-10-13-29(14-11-17)34(32,33)19-6-8-23-18(15-19)16-27-28-23/h3-6,8,15-17,24H,2,7,9-14H2,1H3,(H,27,28)/t24-/m1/s1

SMILES Code: O=C(C1CCN(S(=O)(C2=CC3=C(NN=C3)C=C2)=O)CC1)N([C@@H]4CCC5=C4C=CC=C5F)CCC

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Berizzi AE, Bender AM, Lindsley CW, Conn PJ, Sexton PM, Langmead CJ, Christopoulos A. Structure-Activity Relationships of Pan-Gα(q/11) Coupled Muscarinic Acetylcholine Receptor Positive Allosteric Modulators. ACS Chem Neurosci. 2018 Jul 18;9(7):1818-1828. doi: 10.1021/acschemneuro.8b00136. Epub 2018 Apr 30. PubMed PMID: 29683647; PubMed Central PMCID: PMC6106869.