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MedKoo CAT#: 564369


Description: G907 is a selective MsbA antagonist with bactericidal activity which reveals an unprecedented mechanism of ABC transporter inhibition.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-05-28. Prices are subject to change without notice.

G907 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 564369
Name: G907
Chemical Formula: C26H24ClNO3
Exact Mass: 433.1445
Molecular Weight: 433.93
Elemental Analysis: C, 71.97; H, 5.58; Cl, 8.17; N, 3.23; O, 11.06

Synonym: G-907; G 907; G907

IUPAC/Chemical Name: (E)-3-(6-(1-(2-Chloro-6-cyclopropylphenyl)ethoxy)-4-cyclopropylquinolin-3-yl)acrylic acid


InChi Code: InChI=1S/C26H24ClNO3/c1-15(25-20(16-5-6-16)3-2-4-22(25)27)31-19-10-11-23-21(13-19)26(17-7-8-17)18(14-28-23)9-12-24(29)30/h2-4,9-17H,5-8H2,1H3,(H,29,30)/b12-9+

SMILES Code: O=C(O)/C=C/C1=C(C2CC2)C3=CC(OC(C4=C(C5CC5)C=CC=C4Cl)C)=CC=C3N=C1

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Ho H, Miu A, Alexander MK, Garcia NK, Oh A, Zilberleyb I, Reichelt M, Austin CD, Tam C, Shriver S, Hu H, Labadie SS, Liang J, Wang L, Wang J, Lu Y, Purkey HE, Quinn J, Franke Y, Clark K, Beresini MH, Tan MW, Sellers BD, Maurer T, Koehler MFT, Wecksler AT, Kiefer JR, Verma V, Xu Y, Nishiyama M, Payandeh J, Koth CM. Structural basis for dual-mode inhibition of the ABC transporter MsbA. Nature. 2018 May;557(7704):196-201. doi: 10.1038/s41586-018-0083-5. Epub 2018 May 2. PubMed PMID: 29720648.

2: Curtis MA, Aduse-Opoku J, Slaney JM, Rangarajan M, Booth V, Cridland J, Shepherd P. Characterization of an adherence and antigenic determinant of the ArgI protease of Porphyromonas gingivalis which is present on multiple gene products. Infect Immun. 1996 Jul;64(7):2532-9. PubMed PMID: 8698476; PubMed Central PMCID: PMC174107.