Trimethylcolchicinic acid

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581545

CAS#: 3482-37-9

Description: Trimethylcolchicinic acid is an antimitotic agent disrupting microtubule action through the binding of tubulin and preventing polymerization. Has been shown to stimulate the intrinsic GTPase activity of tubulin. Induces apoptosis and activates the JNK/SAPK signals.

Chemical Structure

Trimethylcolchicinic acid
CAS# 3482-37-9

Theoretical Analysis

MedKoo Cat#: 581545
Name: Trimethylcolchicinic acid
CAS#: 3482-37-9
Chemical Formula: C19H21NO5
Exact Mass: 343.142
Molecular Weight: 343.379
Elemental Analysis: C, 66.46; H, 6.16; N, 4.08; O, 23.30

Price and Availability

Size Price Availability Quantity
50.0mg USD 270.0 2 Weeks
100.0mg USD 420.0 2 Weeks
200.0mg USD 650.0 2 Weeks
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Synonym: Trimethylcolchicinic acid; N-Deacetylcolchiceine; Deacetylcolchiceine; Colchicinic acid, trimethyl-

IUPAC/Chemical Name: (S)-7-Amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxybenzo(a)heptalen-9(5H)-one


InChi Code: InChI=1S/C19H21NO5/c1-23-16-8-10-4-6-13(20)12-9-15(22)14(21)7-5-11(12)17(10)19(25-3)18(16)24-2/h5,7-9,13H,4,6,20H2,1-3H3,(H,21,22)/t13-/m0/s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 343.379 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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