H 151

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584647

CAS#: 941987-60-6

Description: H 151 is a STING antagonist that covalently binds STING at Cys91, blocking palmitoylation and preventing assembly of STING clusters.

Chemical Structure

H 151
CAS# 941987-60-6

Theoretical Analysis

MedKoo Cat#: 584647
Name: H 151
CAS#: 941987-60-6
Chemical Formula: C17H17N3O
Exact Mass: 279.1372
Molecular Weight: 279.343
Elemental Analysis: C, 73.10; H, 6.13; N, 15.04; O, 5.73

Price and Availability

Size Price Availability Quantity
10.0mg USD 340.0 2 Weeks
50.0mg USD 960.0 2 Weeks
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Synonym: H 151; H-151; H151;

IUPAC/Chemical Name: N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea


InChi Code: InChI=1S/C17H17N3O/c1-2-12-7-9-13(10-8-12)19-17(21)20-16-11-18-15-6-4-3-5-14(15)16/h3-11,18H,2H2,1H3,(H2,19,20,21)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934999001

Preparing Stock Solutions

The following data is based on the product molecular weight 279.343 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Haag et al (2018) Targeting STING with covalent small-molecule inhibitors. Nature 559 269 PMID: 29973723

H 151

10.0mg / USD 340.0