Vinglycinate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581533

CAS#: 865-24-7

Description: Vinglycinate is a biochemical.


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is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 581533
Name: Vinglycinate
CAS#: 865-24-7
Chemical Formula:
Exact Mass:
Molecular Weight:
Elemental Analysis:


Synonym: Vinglycinate; Vinglicinato; Vinglycinatum

IUPAC/Chemical Name: methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-((dimethylglycyl)oxy)-3a-ethyl-9-((5S,7R,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate

InChi Key: YNSIUGHLISOIRQ-XGNYHKEJSA-N

InChi Code: 1S/C48H63N5O9/c1-9-44(57)24-29-25-47(42(55)60-7,38-31(16-20-52(26-29)28-44)30-14-11-12-15-34(30)49-38)33-22-32-35(23-36(33)59-6)51(5)40-46(32)18-21-53-19-13-17-45(10-2,39(46)53)41(48(40,58)43(56)61-8)62-37(54)27-50(3)4/h11-15,17,22-23,29,39-41,49,57-58H,9-10,16,18-21,24-28H2,1-8H3/t29-,39-,40+,41+,44-,45+,46+,47-,48-/m0/s1

SMILES Code: CC[C@@]1(C[C@H]2C[C@@](c3c(c4ccccc4[nH]3)CCN(C2)C1)(c5cc6c(cc5OC)N([C@@H]7[C@]68CCN9[C@H]8[C@@](C=CC9)([C@H]([C@@]7(C(=O)OC)O)OC(=O)CN(C)C)CC)C)C(=O)OC)O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Armstrong JG, Dyke RW, Fouts PJ, Hawthorne JJ, Jansen CJ Jr, Peabody AM. Initial clinical experience with vinglycinate sulfate, a molecular modification of vinblastine. Cancer Res. 1967 Feb;27(2):221-7. PubMed PMID: 5335120.

2: Johnson IS, Hargrove WW, Harris PN, Wright HF, Boder GB. Preclinical studies with vinglycinate, one of a series of chemically derived analogs of vinblastine. Cancer Res. 1966 Dec;26(12):2431-6. PubMed PMID: 5955595.