BTZO-1
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MedKoo CAT#: 564294

CAS#: 99420-15-2

Description: BTZO-1 is an activator of the glutathione S-transferase Ya subunit (GST Ya) gene ARE by interacting with MIF.


Price and Availability

Size Price Shipping out time Quantity
5mg USD 280 2 Weeks
25mg USD 680 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-04-07. Prices are subject to change without notice.

BTZO-1, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data, and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564294
Name: BTZO-1
CAS#: 99420-15-2
Chemical Formula: C13H8N2OS
Exact Mass: 240.0357
Molecular Weight: 240.28
Elemental Analysis: C, 64.98; H, 3.36; N, 11.66; O, 6.66; S, 13.34


Synonym: BTZO1; BTZO 1; BTZO-1

IUPAC/Chemical Name: 2-Pyridin-2-yl-1,3-benzothiazin-4-one

InChi Key: GBAKVEWPYUIGHN-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H8N2OS/c16-12-9-5-1-2-7-11(9)17-13(15-12)10-6-3-4-8-14-10/h1-8H

SMILES Code: O=C1N=C(C2=NC=CC=C2)SC3=CC=CC=C13


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Kimura H, Sato Y, Tajima Y, Suzuki H, Yukitake H, Imaeda T, Kajino M, Oki H, Takizawa M, Tanida S. BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression. Chem Biol. 2010 Dec 22;17(12):1282-94. doi: 10.1016/j.chembiol.2010.10.011. PubMed PMID: 21168764.

2: Yukitake H, Takizawa M, Kimura H. Macrophage Migration Inhibitory Factor as an Emerging Drug Target to Regulate Antioxidant Response Element System. Oxid Med Cell Longev. 2017;2017:8584930. doi: 10.1155/2017/8584930. Epub 2017 Jan 16. Review. PubMed PMID: 28191280; PubMed Central PMCID: PMC5278225.