17-Oxolupanine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 528047

CAS#: 4697-83-0

Description: 17-Oxolupanine is a bioactive chemical.


Chemical Structure

img
17-Oxolupanine
CAS# 4697-83-0

Theoretical Analysis

MedKoo Cat#: 528047
Name: 17-Oxolupanine
CAS#: 4697-83-0
Chemical Formula: C15H22N2O2
Exact Mass: 262.17
Molecular Weight: 262.353
Elemental Analysis: C, 68.67; H, 8.45; N, 10.68; O, 12.20

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: 17-Oxolupanine

IUPAC/Chemical Name: 7,14-Methano-4H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine-4,13(14H)-dione, decahydro-, (7S-(7alpha,7abeta,14alpha,14aalpha))-

InChi Key: HBYSMHYHSFSCED-QNWHQSFQSA-N

InChi Code: InChI=1S/C15H22N2O2/c18-14-6-3-5-13-11-8-10(9-17(13)14)12-4-1-2-7-16(12)15(11)19/h10-13H,1-9H2/t10-,11+,12-,13+/m0/s1

SMILES Code: O=C1CCC[C@@]([C@@]2([H])C3)([H])N1C[C@@]3([H])[C@@](CCCC4)([H])N4C2=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 262.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Parmaki S, Vyrides I, Vasquez MI, Hartman V, Zacharia I, Hadjiadamou I, Barbeitos CBM, Ferreira FC, Afonso CAM, Drouza C, Koutinas M. Bioconversion of alkaloids to high-value chemicals: Comparative analysis of newly isolated lupanine degrading strains. Chemosphere. 2018 Feb;193:50-59. doi: 10.1016/j.chemosphere.2017.10.165. Epub 2017 Oct 30. PubMed PMID: 29126065.

2: Adler LS, Wink M. Transfer of quinolizidine alkaloids from hosts to hemiparasites in two Castilleja-Lupinus associations: analysis of floral and vegetative tissues. Biochem Syst Ecol. 2001 Jun;29(6):551-561. PubMed PMID: 11336806.

3: Wink M, Witte L, Hartmann T, Theuring C, Volz V. Accumulation of quinolizidine alkaloids in plants and cell suspension cultures: genera lupinus, cytisus, baptisia, genista, laburnum, and sophora. Planta Med. 1983 Aug;48(8):253-7. PubMed PMID: 17404991.

4: Wink M, Witte L, Hartmann T. Quinolizidine alkaloid composition of plants and of photomixotrophic cell suspension cultures of Sarothamnus scoparius and Orobanche rapum-genistae. Planta Med. 1981 Dec;43(4):342-52. PubMed PMID: 17402058.

5: Keeler RF, Gross R. The total alkaloid and anagyrine contents of some bitter and sweet selections of lupin species used as food. J Environ Pathol Toxicol. 1980 Jun-Jul;3(5-6):333-40. PubMed PMID: 7441088.

6: Mazur M, Polakowski P, Szadowska A. [Pharmacologic studies on 17-oxolupanine, lupanine aminooxide and 17-hydroxylupanine]. Acta Physiol Pol. 1966 Mar-Apr;17(2):311-20. Polish. PubMed PMID: 5945524.