WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 564235
CAS#: 1430218-51-1
Description: VI-16832 is a broad spectrum type-I kinase inhibitor.
MedKoo Cat#: 564235
Name: VI-16832
CAS#: 1430218-51-1
Chemical Formula: C22H25N5O2
Exact Mass: 391.2008
Molecular Weight: 391.48
Elemental Analysis: C, 67.50; H, 6.44; N, 17.89; O, 8.17
Synonym: VI16832; VI 16832; VI-16832
IUPAC/Chemical Name: 2-[4-(2-Aminoethoxy)anilino]-8-(3-bicyclo[2.2.1]heptanyl)pyrido[2,3-d]pyrimidin-7-one
InChi Key: RCSLGYIVHUXZCI-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H25N5O2/c23-9-10-29-18-6-4-17(5-7-18)25-22-24-13-16-3-8-20(28)27(21(16)26-22)19-12-14-1-2-15(19)11-14/h3-8,13-15,19H,1-2,9-12,23H2,(H,24,25,26)
SMILES Code: O=C1C=CC2=CN=C(NC3=CC=C(OCCN)C=C3)N=C2N1C4CC5CCC4C5
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 391.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Oppermann FS, Gnad F, Olsen JV, Hornberger R, Greff Z, Kéri G, Mann M, Daub H. Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics. 2009 Jul;8(7):1751-64. doi: 10.1074/mcp.M800588-MCP200. Epub 2009 Apr 15. PubMed PMID: 19369195; PubMed Central PMCID: PMC2709199.
