By241

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564201

CAS#: NONE

Description: By241 is a potent inhibitor of tumor growth mainly through ROS-mediated mechanisms.


Price and Availability

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By241 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564201
Name: By241
CAS#: NONE
Chemical Formula: C32H35N3O4
Exact Mass: 525.2628
Molecular Weight: 525.65
Elemental Analysis: C, 73.12; H, 6.71; N, 7.99; O, 12.17


Synonym: By-241; By 241; By241

IUPAC/Chemical Name: (3S,4'S,6a'R,6b'S,8a'S,13a'S,13b'R)-10'-Amino-9'-cyano-6a',8a'-dimethyl-2-oxo-3',4',5',6',6a',6b',7',8',8a',13',13a',13b'-dodecahydro-1'H-spiro[indoline-3,12'-naphtho[2',1':4,5]indeno[2,1-c]pyran]-4'-yl acetate

InChi Key: OMBHFVJRCSLUHJ-ICEDAUCJSA-N

InChi Code: InChI=1S/C32H35N3O4/c1-17(36)38-19-10-12-30(2)18(14-19)8-9-20-22(30)11-13-31(3)24(20)15-25-27(31)21(16-33)28(34)39-32(25)23-6-4-5-7-26(23)35-29(32)37/h4-8,19-20,22,24H,9-15,34H2,1-3H3,(H,35,37)/t19-,20+,22-,24-,30-,31-,32+/m0/s1

SMILES Code: CC(O[C@@H](CC[C@@]12C)CC1=CC[C@@]([C@]2([H])CC[C@@]34C)([H])[C@]3([H])CC5=C4C(C#N)=C(N)O[C@]65C(NC7=C6C=CC=C7)=O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Shi XJ, Yu B, Wang JW, Qi PP, Tang K, Huang X, Liu HM. Structurally novel steroidal spirooxindole by241 potently inhibits tumor growth mainly through ROS-mediated mechanisms. Sci Rep. 2016 Aug 16;6:31607. doi: 10.1038/srep31607. PubMed PMID: 27527552; PubMed Central PMCID: PMC4985843.